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Sciatica clinical trials recruiting in the U.S.

5 studies for Sciatica are recruiting participants at sites across the United States.

Sciatica is a symptom of a problem with the sciatic nerve causing pain, weakness, numbness, or tingling. Read about causes, tests, and treatment.

Recently updated studies

Study to Evaluate Safety of C-1101 Versus Sterile Saline in Adults With Chronic Painful Lumbosacral Radiculopathy

RecruitingPhase 1
Ages 18 to 70 · All sexes · Updated Nov 12, 2026 · NCT07264270

A Multicomponent Intervention for Patients With Lumbosacral Radiculopathy: Move-MORE

Recruiting
Ages 18 to 75 · All sexes · Updated Aug 26, 2026 · NCT07125027

Procedural Framing and Epidural Steroid Injection Outcomes

Recruiting
All ages · All sexes · Updated Aug 18, 2026 · NCT07498140

Brain Mechanisms Supporting Cannabis-induced Pain Relief

RecruitingEarly phase 1Healthy volunteers welcome
Ages 21 to 65 · All sexes · Updated Jun 3, 2026 · NCT04982965

Comparing Ultrasound-Guided Transgluteal Nerve Block to Standard Care

Recruiting
Ages 18 and older · All sexes · Updated Jun 2, 2026 · NCT07397117

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.