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Sclerosing Cholangitis clinical trials recruiting in the U.S.

17 studies for Sclerosing Cholangitis are recruiting participants at sites across the United States.

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Recently updated studies

A Study to Assess How Well and Safely Elafibranor Works in Adult Participants With Primary Sclerosing Cholangitis

RecruitingPhase 3
Ages 18 to 75 · All sexes · Updated Oct 1, 2026 · NCT07387549

Unraveling the Mechanisms Underlying Primary Sclerosing Cholangitis Through a Multidisciplinary, Integrative Research Approach

RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 90 · All sexes · Updated Sep 22, 2026 · NCT04685200

A-LiNK: Improving Outcomes in Autoimmune Liver Disease

RecruitingObservational study
All ages · All sexes · Updated Aug 19, 2026 · NCT05750498

MRI Biomarkers in as Predictor of Clinical Endpoints in Pediatric Autoimmune Liver Disease

RecruitingObservational study
Ages 6 to 23 · All sexes · Updated Aug 19, 2026 · NCT03178630

MRI Based Biomarkers in Pediatric Autoimmune Liver Disease

RecruitingObservational study
Ages 6 to 23 · All sexes · Updated Aug 19, 2026 · NCT03175471

Detoxification of the Liver In PSC (Dolphin)

RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Jul 21, 2026 · NCT05835505

Pharmacologic Approaches to Preventing Primary Sclerosing Cholangitis Recurrence After Liver Transplantation

RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Jul 17, 2026 · NCT06905054

Primary Sclerosing Cholangitis in Children

RecruitingObservational study
Ages 2 to 25 · All sexes · Updated Jul 14, 2026 · NCT04181138

Evaluation of an Oral Microbiota-based Therapeutic as a Treatment Option for PSC

RecruitingEarly phase 1
Ages 18 to 76 · All sexes · Updated May 20, 2026 · NCT06197308

A Study of TAK-781 in Healthy Volunteers and in Participants With Non-Cirrhotic Primary Sclerosing Cholangitis (PSC)

RecruitingPhase 1Healthy volunteers welcome
Ages 18 to 68 · All sexes · Updated Mar 5, 2026 · NCT07229911

Statin Therapy in Primary Sclerosing Cholangitis (PSC): a Multi-omics Study

RecruitingEarly phase 1Healthy volunteers welcome
Ages 18 to 80 · All sexes · Updated Feb 27, 2026 · NCT05912387

Biobank for Cholestatic Liver Diseases.

RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 85 · All sexes · Updated Feb 17, 2026 · NCT03445585

Characterization of Biliary Cell-derived Organoids From Bile of PSC and Non-PSC Patients

RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 85 · All sexes · Updated Feb 17, 2026 · NCT04753996

A Study of SIPLIZUMAB in AILD and LT Patients

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 24, 2025 · NCT06455280

A Study to Assess the Safety and Efficacy of LB-P8 in Patients With PSC

RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Oct 24, 2025 · NCT06699121

Oral Hymecromone to Treat Adolescents and Adults With Primary Sclerosing Cholangitis.

RecruitingPhase 2
Ages 14 to 75 · All sexes · Updated Jun 13, 2025 · NCT05295680

Treating Primary Sclerosing Cholangitis and Biliary Atresia With Vancomycin

RecruitingPhase 1Healthy volunteers welcome
2 Weeks – 40 Years · All sexes · Updated Nov 15, 2016 · NCT02137668

From ClinicalTrials.gov, data retrieved Oct 2, 2026. Each study sets its own eligibility; the study team decides who can join.