Home โบ Seizures
Seizures clinical trials recruiting in the U.S.
57 studies for Seizures are recruiting participants at sites across the United States.
Seizures are caused by sudden, abnormal electrical activity in the brain. They can be mild or severe. Learn about the types, causes, and treatments.
Cities with the most studies
- Washington, DC13 studies
- New York City, NY12 studies
- Philadelphia, PA11 studies
- Boston, MA8 studies
- Birmingham, AL7 studies
- Chicago, IL7 studies
- Dallas, TX7 studies
- Houston, TX7 studies
- Cincinnati, OH7 studies
- Durham, NC6 studies
- Aurora, CO6 studies
- Miami, FL6 studies
- Clifton, NJ5 studies
- Los Angeles, CA5 studies
- San Francisco, CA5 studies
- San Diego, CA5 studies
- Salt Lake City, UT5 studies
- Phoenix, AZ5 studies
- Portland, OR5 studies
- Columbus, OH5 studies
- Cleveland, OH4 studies
- Boise, ID4 studies
- Orange, CA4 studies
- Mountain View, CA4 studies
- Little Rock, AR4 studies
- Seattle, WA4 studies
- Charlotte, NC4 studies
- New Haven, CT4 studies
- Orlando, FL4 studies
- Nashville, TN4 studies
- Jacksonville, FL4 studies
- Atlanta, GA3 studies
- Milwaukee, WI3 studies
- Tucson, AZ3 studies
- Detroit, MI3 studies
- Winston-Salem, NC3 studies
- St. Louis, MO3 studies
- Austin, TX3 studies
- Edison, NJ3 studies
- Tampa, FL3 studies
By state
- Alabama8 studies
- Arizona7 studies
- Arkansas5 studies
- California16 studies
- Colorado7 studies
- Connecticut4 studies
- Florida17 studies
- Georgia4 studies
- Idaho4 studies
- Illinois8 studies
- Kentucky4 studies
- Maryland11 studies
- Massachusetts9 studies
- Michigan6 studies
- Minnesota5 studies
- Missouri5 studies
- New Jersey8 studies
- New York16 studies
- North Carolina11 studies
- Ohio13 studies
- Oregon5 studies
- Pennsylvania12 studies
- Tennessee6 studies
- Texas14 studies
- Utah6 studies
- Virginia3 studies
- Washington4 studies
- Wisconsin4 studies
Recently updated studies
Investigation of Blood-Brain-Barrier Breakdown Using Manganese Magnetic Resonance Imaging in Drug-Resistant Epilepsy
RecruitingPhase 1
Ages 18 to 60 ยท All sexes ยท Updated Sep 28, 2026 ยท NCT02531880Study Evaluating the Efficacy and Safety of RAP-219 in Adult Participants With Focal Seizures FOCUS-1
RecruitingPhase 3
Ages 18 to 75 ยท All sexes ยท Updated Sep 25, 2026 ยท NCT07563881Modulating Movement Intention Via Cortical Stimulation
RecruitingHealthy volunteers welcome
Ages 18 to 65 ยท All sexes ยท Updated Sep 25, 2026 ยท NCT03233399Optimizing Therapy in Epilepsy Using Seizure Forecasts Via EEG and Wearables
RecruitingEarly phase 1Mentions payment for participants
Ages 18 to 75 ยท All sexes ยท Updated Sep 25, 2026 ยท NCT07012148Natural History of Treated Neurocysticercosis and Long-Term Outcomes
RecruitingObservational studyHealthy volunteers welcome
Ages 3 to 99 ยท All sexes ยท Updated Sep 22, 2026 ยท NCT00001205Acute Effects of Focused Ultrasound Modulation on EEG Behavior in Status Epilepticus Patients
Recruiting
Ages 19 to 85 ยท All sexes ยท Updated Sep 21, 2026 ยท NCT05784805Investigating Epilepsy: Screening and Evaluation
RecruitingObservational study
Ages 8 to 110 ยท All sexes ยท Updated Sep 21, 2026 ยท NCT03478852Ketogenic Therapy Effects on Electrical and Metabolic Abnormalities in Epilepsy
Recruiting
Up to age 50 ยท All sexes ยท Updated Sep 17, 2026 ยท NCT02216500A Study of EPX-100 (Clemizole Hydrochloride) in Participants With Dravet Syndrome
RecruitingPhase 3
Ages 2 and older ยท All sexes ยท Updated Sep 15, 2026 ยท NCT04462770A Safety, Tolerability, and Preliminary Efficacy of Low-intensity Focused Ultrasound Neuromodulation in Patients With Drug-resistant Epilepsy
RecruitingPhase 1/2
Ages 18 and older ยท All sexes ยท Updated Sep 15, 2026 ยท NCT06388707An Efficacy and Safety Study of Clemizole HCl in Patients With Lennox-Gastaut Syndrome
RecruitingPhase 3
Ages 2 to 55 ยท All sexes ยท Updated Sep 15, 2026 ยท NCT05066217Prospective Natural History Study of POLG Disease
RecruitingObservational study
All ages ยท All sexes ยท Updated Sep 15, 2026 ยท NCT07775872SeizEAR Safety Study
RecruitingHealthy volunteers welcome
Ages 18 to 70 ยท All sexes ยท Updated Sep 14, 2026 ยท NCT07088835Prophylactic Anti-Seizure Medication vs No Anti-Seizure Medication for Patients With Primary Motor Cortex Brain Metastases
RecruitingPhase 2
Ages 18 and older ยท All sexes ยท Updated Sep 8, 2026 ยท NCT07130786Study Evaluating the Efficacy and Safety of RAP-219 in Adult Participants With Focal Seizures
RecruitingPhase 3
Ages 18 to 75 ยท All sexes ยท Updated Sep 2, 2026 ยท NCT07594119Tumor Related Epilepsy
RecruitingObservational study
Ages 8 to 99 ยท All sexes ยท Updated Aug 28, 2026 ยท NCT02639325Retraining and Control Therapy (ReACT): Sense of Control and Symptom Expectations as Targets of a Treatment for PNES
RecruitingHealthy volunteers welcome
Ages 11 to 18 ยท All sexes ยท Updated Aug 26, 2026 ยท NCT05096273A Study to Determine if BHV-7000 is Effective and Safe in Adults With Refractory Focal Onset Epilepsy
RecruitingPhase 2/3
Ages 18 to 75 ยท All sexes ยท Updated Aug 24, 2026 ยท NCT06132893A Study to Evaluate the Efficacy and Safety of Cannabidiol Oral Solution (CBD-OS [GWP42003-P, JZP926]) for the Treatment of Focal-Onset Seizures
RecruitingPhase 1
Ages 12 to 75 ยท All sexes ยท Updated Aug 11, 2026 ยท NCT07233239Outcomes After Planned Discontinuation of AntiSeizure Medication
RecruitingPhase 4
Ages 18 and older ยท All sexes ยท Updated Aug 6, 2026 ยท NCT07750496Comparative Effectiveness of Palliative Surgery Versus Additional Anti-Seizure Medications for Lennox-Gastaut Syndrome
RecruitingObservational study
Up to age 26 ยท All sexes ยท Updated Aug 6, 2026 ยท NCT05374824A Clinical Trial of Elsunersen in Pediatric SCN2A-DEE to Assess Efficacy and Safety
RecruitingPhase 3
1 Day โ 18 Years ยท All sexes ยท Updated Aug 3, 2026 ยท NCT07019922PeRampanel fOr Status ePilEpticus pRophylaxis Post-cardiac Arrest
RecruitingPhase 2
Ages 18 and older ยท All sexes ยท Updated Jul 29, 2026 ยท NCT06401707buRst-supprESsion TO Stop Refractory Status Epilepticus Post-cardiac Arrest
RecruitingPhase 2
Ages 18 and older ยท All sexes ยท Updated Jul 29, 2026 ยท NCT05851391Mapping of Human Cognition
Recruiting
Ages 18 to 75 ยท All sexes ยท Updated Jul 14, 2026 ยท NCT05989893From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.