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Seizures clinical trials recruiting in the U.S.
55 studies for Seizures are recruiting participants at sites across the United States.
Seizures are caused by sudden, abnormal electrical activity in the brain. They can be mild or severe. Learn about the types, causes, and treatments.
Cities with the most studies
- New York City, NY13 studies
- Washington, DC13 studies
- Philadelphia, PA12 studies
- Houston, TX9 studies
- Birmingham, AL8 studies
- Miami, FL7 studies
- Boston, MA7 studies
- Cincinnati, OH6 studies
- San Francisco, CA6 studies
- Durham, NC6 studies
- Dallas, TX6 studies
- Chicago, IL5 studies
- Aurora, CO5 studies
- Orlando, FL5 studies
- Clifton, NJ5 studies
- Cleveland, OH5 studies
- Orange, CA5 studies
- Portland, OR5 studies
- Los Angeles, CA5 studies
- Phoenix, AZ5 studies
- San Diego, CA4 studies
- Nashville, TN4 studies
- Charlotte, NC4 studies
- Seattle, WA4 studies
- Salt Lake City, UT4 studies
- New Haven, CT4 studies
- Detroit, MI4 studies
- Rochester, MN3 studies
- Jacksonville, FL3 studies
- Boise, ID3 studies
- Springfield, IL3 studies
- Atlanta, GA3 studies
- East Pensacola Heights, FL3 studies
- Columbus, OH3 studies
- Omaha, NE3 studies
- Milwaukee, WI3 studies
- Tucson, AZ3 studies
- Little Rock, AR3 studies
- Louisville, KY3 studies
- Mountain View, CA3 studies
By state
- Alabama9 studies
- Arizona7 studies
- Arkansas4 studies
- California16 studies
- Colorado6 studies
- Connecticut4 studies
- Florida15 studies
- Georgia3 studies
- Idaho3 studies
- Illinois8 studies
- Kentucky4 studies
- Maryland11 studies
- Massachusetts8 studies
- Michigan6 studies
- Minnesota4 studies
- Missouri3 studies
- Nebraska3 studies
- New Jersey8 studies
- New York16 studies
- North Carolina11 studies
- Ohio12 studies
- Oregon5 studies
- Pennsylvania13 studies
- Tennessee6 studies
- Texas15 studies
- Utah5 studies
- Virginia3 studies
- Washington4 studies
- Wisconsin3 studies
Recently updated studies
Study Evaluating the Efficacy and Safety of RAP-219 in Adult Participants With Focal Seizures FOCUS-1
RecruitingPhase 3
Ages 18 to 75 ยท All sexes ยท Updated Nov 12, 2026 ยท NCT07563881Study Evaluating the Efficacy and Safety of RAP-219 in Adult Participants With Focal Seizures
RecruitingPhase 3
Ages 18 to 75 ยท All sexes ยท Updated Nov 12, 2026 ยท NCT07594119Tumor Related Epilepsy
RecruitingObservational study
Ages 8 to 99 ยท All sexes ยท Updated Nov 12, 2026 ยท NCT02639325Investigate Efficacy and Safety of Carisbamate as Adjunctive Treatment for Seizures Associated With LGS in Children and Adults
RecruitingPhase 3
Ages 4 to 55 ยท All sexes ยท Updated Nov 6, 2026 ยท NCT05219617Genetic Markers of Cardiovascular Disease in Epilepsy
RecruitingObservational study
Ages 18 to 50 ยท All sexes ยท Updated Nov 3, 2026 ยท NCT02824822A Randomized Study of XEN1101 Versus Placebo in Focal-Onset Seizures (X-TOLE3)
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Nov 2, 2026 ยท NCT05716100HOBSCOTCH-YOUTH and Young Adults
Recruiting
Ages 13 to 29 ยท All sexes ยท Updated Nov 2, 2026 ยท NCT07735715Mapping of Human Cognition
Recruiting
Ages 18 to 75 ยท All sexes ยท Updated Nov 2, 2026 ยท NCT05989893Study of NRTX-1001 Neural Cell Therapy in Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy (EPIC (EPIlepsy Cell Therapy))
RecruitingPhase 3
Ages 18 to 75 ยท All sexes ยท Updated Oct 30, 2026 ยท NCT05135091Natural History of Treated Neurocysticercosis and Long-Term Outcomes
RecruitingObservational studyHealthy volunteers welcome
Ages 3 to 99 ยท All sexes ยท Updated Oct 29, 2026 ยท NCT00001205Investigation of Blood-Brain-Barrier Breakdown Using Manganese Magnetic Resonance Imaging in Drug-Resistant Epilepsy
RecruitingPhase 1
Ages 18 to 60 ยท All sexes ยท Updated Oct 29, 2026 ยท NCT02531880A Study to Evaluate the Efficacy and Safety of Cannabidiol Oral Solution (CBD-OS [GWP42003-P, JZP926]) for the Treatment of Focal-Onset Seizures
RecruitingPhase 1
Ages 12 to 75 ยท All sexes ยท Updated Oct 29, 2026 ยท NCT07233239A Study of EPX-100 (Clemizole Hydrochloride) in Participants With Dravet Syndrome
RecruitingPhase 3
Ages 2 and older ยท All sexes ยท Updated Oct 29, 2026 ยท NCT04462770Investigating Epilepsy: Screening and Evaluation
RecruitingObservational study
Ages 8 to 110 ยท All sexes ยท Updated Oct 26, 2026 ยท NCT03478852Oxygen Toxicity: Mechanisms in Humans
RecruitingHealthy volunteers welcome
Ages 18 to 45 ยท All sexes ยท Updated Oct 21, 2026 ยท NCT05761756Ear-Seizure Detection (EarSD) Study
RecruitingHealthy volunteers welcome
Ages 18 and older ยท All sexes ยท Updated Oct 14, 2026 ยท NCT06598189Clinical and Electrographic Changes in Responsive Neurostimulation System (RNS) Patients With Acupuncture Treatment
Recruiting
Ages 15 to 60 ยท All sexes ยท Updated Oct 13, 2026 ยท NCT04677751An Efficacy and Safety Study of Clemizole HCl in Patients With Lennox-Gastaut Syndrome
RecruitingPhase 3
Ages 2 to 55 ยท All sexes ยท Updated Oct 9, 2026 ยท NCT05066217Pharmacological Modulation of Brain Oscillations in Memory Processing
RecruitingEarly phase 1Healthy volunteers welcome
Ages 18 to 55 ยท All sexes ยท Updated Oct 5, 2026 ยท NCT05594017RENAISSANCE 2: SPN-817 Phase 2, Double-Blind, Placebo-Controlled Study in Adults With Focal Onset Seizures
RecruitingPhase 2
Ages 18 to 70 ยท All sexes ยท Updated Oct 1, 2026 ยท NCT06798896Optimizing Therapy in Epilepsy Using Seizure Forecasts Via EEG and Wearables
RecruitingEarly phase 1Mentions payment for participants
Ages 18 to 75 ยท All sexes ยท Updated Sep 25, 2026 ยท NCT07012148Modulating Movement Intention Via Cortical Stimulation
RecruitingHealthy volunteers welcome
Ages 18 to 65 ยท All sexes ยท Updated Sep 25, 2026 ยท NCT03233399Acute Effects of Focused Ultrasound Modulation on EEG Behavior in Status Epilepticus Patients
Recruiting
Ages 19 to 85 ยท All sexes ยท Updated Sep 21, 2026 ยท NCT05784805Ketogenic Therapy Effects on Electrical and Metabolic Abnormalities in Epilepsy
Recruiting
Up to age 50 ยท All sexes ยท Updated Sep 17, 2026 ยท NCT02216500Prospective Natural History Study of POLG Disease
RecruitingObservational study
All ages ยท All sexes ยท Updated Sep 15, 2026 ยท NCT07775872From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.