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Sexually Transmitted Infections clinical trials recruiting in the U.S.
19 studies for Sexually Transmitted Infections are recruiting participants at sites across the United States.
Sexually transmitted infections (STIs) are passed from person to person during sexual contact. Testing, vaccines, and prevention behaviors can lower your risk.
Cities with the most studies
By state
- California5 studies
- District of Columbia5 studies
- Florida3 studies
- Georgia4 studies
- Maryland3 studies
- North Carolina3 studies
- Pennsylvania3 studies
Recently updated studies
This Study Evaluates the ALPCO Syphilis-T and Syphilis-NT CLIA Kits for Detecting Syphilis Antibodies in Serum and Plasma. Samples From At-risk, HIV-positive, Pregnant, and Healthy Individuals Will Assess Assay Performance Versus Established Comparator Tests.
RecruitingObservational studyHealthy volunteers welcome
Ages 13 and older · All sexes · Updated Sep 16, 2026 · NCT07089836Improving Maternal and Child Health Through Point-of-care STI Testing
RecruitingHealthy volunteers welcome
All ages · Women · Updated Aug 19, 2026 · NCT07290439Evaluation of the Q-Pad hrHPV Test System for Identifying Precancer
RecruitingHealthy volunteers welcome
Ages 25 and older · Women · Updated Jul 24, 2026 · NCT07281599Health-E You Efficacy Trial for Male Adolescents
RecruitingHealthy volunteers welcome
Ages 13 to 21 · Men · Updated Jul 15, 2026 · NCT06525064Improving Alcohol and Substance Use Care Access, Outcome, Equity During the Reproductive Years
Recruiting
Ages 18 and older · All sexes · Updated Jun 15, 2026 · NCT05910580Appalachian Partnership to Reduce Disparities (Aim 2)
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated May 26, 2026 · NCT04378439Gathering Online for Dialogue and Discussion to Enhance Social Support
RecruitingHealthy volunteers welcome
Ages 18 to 30 · All sexes · Updated May 19, 2026 · NCT05753683Doxycycline Prophylaxis for Prevention of Sexually Transmitted Infections
RecruitingPhase 4
Ages 13 to 29 · Women · Updated May 15, 2026 · NCT06738407Point of Care STI Testing
Recruiting
Ages 16 to 24 · All sexes · Updated May 5, 2026 · NCT06844045"Sexual Health Assessment of TinidaZole Against M. Genitalium (SHAZAM)"
RecruitingPhase 2
Ages 18 and older · Men · Updated May 4, 2026 · NCT07088419Got Doxy- 'Flipping the Script' on STI PEP
RecruitingPhase 4Healthy volunteers welcome
Ages 18 and older · Men · Updated Apr 30, 2026 · NCT07215325IMARA for Black Male Caregivers and Girls Empowerment (IMAGE)
RecruitingHealthy volunteers welcome
Ages 13 and older · All sexes · Updated Apr 17, 2026 · NCT06266416California MEPS Hub
RecruitingHealthy volunteers welcome
Ages 18 to 59 · Men · Updated Apr 3, 2026 · NCT07433985Health Information Technology to Reduce Disparities in Adolescent Health Outcomes: A Pragmatic Trial
RecruitingHealthy volunteers welcome
Ages 15 to 21 · All sexes · Updated Mar 18, 2026 · NCT04372875Assessing Acceptability and Feasibiity of STI Self-swab Testing, to be Offered at the Time of Telemed Medication Abortion Provision
RecruitingHealthy volunteers welcome
Ages 14 and older · Women · Updated Jun 26, 2025 · NCT06951438Evaluation of Parent Toolkit 2.0 (Morehouse Family Health Study)
RecruitingHealthy volunteers welcome
Ages 12 to 15 · All sexes · Updated Apr 30, 2025 · NCT06579781Using Mobile Health (mHealth) to Improve STI Treatment Adherence Among Adolescents
Recruiting
Ages 15 to 21 · All sexes · Updated Aug 21, 2024 · NCT04372485Evaluation of the SafeSpace App Intervention
RecruitingHealthy volunteers welcome
Ages 14 to 18 · Women · Updated Nov 21, 2023 · NCT06043596Comparing Mobile Health Strategies to Improve Pre-exposure Prophylaxis Use (PrEP) for HIV Prevention
RecruitingHealthy volunteers welcome
Ages 15 and older · All sexes · Updated Sep 28, 2022 · NCT04855773From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.