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Thyroid Cancer clinical trials recruiting in the U.S.

48 studies for Thyroid Cancer are recruiting participants at sites across the United States.

Your thyroid is a butterfly-shaped gland in your neck. There are several thyroid cancer types with different treatments. Discover options available.

Cities with the most studies

By state

Recently updated studies

The Role of 68-Gallium-DOTATATE-PET/CT in the Imaging of Metastatic Thyroid Cancer

RecruitingPhase 2
Ages 18 to 98 · All sexes · Updated Nov 12, 2026 · NCT04927416

DICER1-related Pleuropulmonary Blastoma Cancer Predisposition Syndrome: A Natural History Study

RecruitingObservational studyHealthy volunteers welcome
1 Month – 99 Years · All sexes · Updated Nov 12, 2026 · NCT01247597

Studies on Tumors of the Thyroid

RecruitingObservational study
6 Months – 98 Years · All sexes · Updated Nov 9, 2026 · NCT00001160

Nanosecond Pulsed Field Ablation in the Management of T1N0M0 Papillary Thyroid Carcinoma

Recruiting
Ages 18 and older · All sexes · Updated Nov 9, 2026 · NCT07218315

Zanzalintinib for the Treatment of Advanced Thyroid Cancer Before Surgery

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Nov 5, 2026 · NCT06959511

Evaluation of DNA Methylation Signatures for the Diagnosis and Management of Thyroid Nodules

Recruiting
Ages 18 and older · All sexes · Updated Nov 5, 2026 · NCT05229341

Genetic Analysis of Pheochromocytomas, Paragangliomas and Associated Conditions

RecruitingObservational studyHealthy volunteers welcome
All ages · All sexes · Updated Nov 5, 2026 · NCT03160274

Prospective Comprehensive Molecular Analysis of Endocrine Neoplasms

RecruitingObservational study
Ages 4 and older · All sexes · Updated Nov 5, 2026 · NCT01005654

Active Surveillance of Papillary Thyroid Microcarcinoma

Recruiting
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT02609685

cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease

RecruitingObservational studyHealthy volunteers welcome
Ages 40 and older · All sexes · Updated Nov 4, 2026 · NCT05366881

Artificial Tears to Prevent Nasolacrimal Duct Obstruction in Patients Treated With Radioactive Iodine for Thyroid Cancer

RecruitingPhase 3Healthy volunteers welcome
Ages 18 and older · All sexes · Updated Nov 3, 2026 · NCT05999630

The Use of 124-I-PET/CT Whole Body and Lesional Dosimetry in Differentiated Thyroid Cancer

RecruitingPhase 2
Ages 18 to 90 · All sexes · Updated Oct 29, 2026 · NCT03841617

International PPB/DICER1 Registry

RecruitingObservational studyHealthy volunteers welcome
0 Minutes – 100 Years · All sexes · Updated Oct 26, 2026 · NCT03382158

Larotrectinib to Enhance RAI Avidity in Differentiated Thyroid Cancer

RecruitingPhase 2
Ages 2 to 99 · All sexes · Updated Oct 21, 2026 · NCT05783323

Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors

RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 15, 2026 · NCT06239194

A Study of Avutometinib and Defactinib in People With Thyroid Cancer

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 15, 2026 · NCT06007924

Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies

RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 13, 2026 · NCT05786924

XL092 and Cemiplimab in BRAF WT Thyroid Cancer

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT06902376

DESTINY-PANTUMOUR04

RecruitingObservational study
Ages 18 to 130 · All sexes · Updated Sep 25, 2026 · NCT07124000

Lesion Dosimetry With Iodine-124 in Metastatic Thyroid Carcinoma

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT03647358

A Study of Meaning-Centered Therapy for Mexican Adults With Advanced Cancer

Recruiting
Ages 18 and older · All sexes · Updated Aug 3, 2026 · NCT07225309

Cyclophosphamide and Sirolimus for the Treatment of Metastatic, RAI-refractory, Differentiated Thyroid Cancer

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jul 31, 2026 · NCT03099356

Selpercatinib Pre-RAI in Patients With RET Fusion Thyroid Cancer (RAISE)

RecruitingPhase 2
Ages 2 to 25 · All sexes · Updated Jul 24, 2026 · NCT06458036

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.