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Triple-Negative Breast Cancer clinical trials in Michigan

29 studies for Triple-Negative Breast Cancer are looking for participants at sites in Michigan.

Cities in Michigan

177Lu-BetaBart in Patients With Relapsed/Refractory, Locally Advanced Inoperable, or Metastatic Solid Tumors

  • BAMF Health, Grand Rapids
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT07189871

Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR (MK-2870-012)

  • University of Michigan ( Site 0103), Ann Arbor
  • Henry Ford Health ( Site 0010), Detroit
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06393374

A Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Triple-Negative Breast Cancer (MK-2870-011/TroFuse-011)

  • Cancer & Hematology Centers of Western Michigan ( Site 0026), Grand Rapids
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06841354

A Study of [225Ac]Ac-AKY-1189 in Patients With Solid Tumors

  • BAMF Health, Grand Rapids
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07020117

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

  • Karmanos Cancer Institute, Detroit
RecruitingPhase 1/2
Ages 12 and older · All sexes · Updated Sep 15, 2026 · NCT04585750

Phase 1 Study of a Self-amplifying RNA Vaccine (ITI-5000) in Stage 2-3 Triple Negative Breast Cancer

  • START Midwest, Grand Rapids
RecruitingPhase 1
Ages 18 and older · Women · Updated Sep 10, 2026 · NCT07652242

Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)

  • Cancer and Hematology Centers of Western Michigan, Grand Rapids
  • William Beaumont Hospital, Royal Oak
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT05633654

A Study of Sofe-M in Participants With Selected Advanced Solid Tumors

  • South Texas Accelerated Research Therapeutics (START) Midwest, Grand Rapids
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT06400472

A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors

  • START Midwest Cancer and Hematology Centers of W Michigan, Grand Rapids
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT06465069

Evaluating Minimal Residual Disease (MRD) Through Longitudinal Circulating Tumor DNA (ctDNA) Profiling in Breast Malignancies

  • Trinity Health, Ann Arbor
RecruitingObservational study
Ages 18 to 99 · All sexes · Updated Sep 3, 2026 · NCT07211178

A Study With NKT5097 for Adults With Advanced/Metastatic Solid Tumors

  • South Texas Accelerated Research Therapeutics (START) Midwest, Grand Rapids
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 28, 2026 · NCT07029399

A Study to Investigate Safety of AZD6750 in Adult Participants With Select Advanced or Metastatic Solid Tumors

  • Research Site, Grand Rapids
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT07115043

Study to Assess GTAEXS617 in Participants With Advanced Solid Tumors

  • START Midwest, Grand Rapids
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 13, 2026 · NCT05985655

A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01)

  • Henry Ford Cancer- Detroit (Brigitte Harris Cancer Pavilion), Detroit
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Aug 10, 2026 · NCT06926868

Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)

  • Karmanos Cancer Institute, Detroit
  • START Midwest, Grand Rapids
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 4, 2026 · NCT05579366

A Phase 1 Study of PLN-101095 in Adults With Advanced or Metastatic Solid Tumors

  • South Texas Accelerated Research Therapeutics (START), Grand Rapids
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 3, 2026 · NCT06270706

Phase I Study of [177Lu]Lu-NNS309 in Patients With Pancreatic, Lung, Breast and Colorectal Cancers

  • BAMF Health, Grand Rapids
RecruitingPhase 1
Ages 18 to 100 · All sexes · Updated Jul 29, 2026 · NCT06562192

A Study to Learn About the Study Medicine Called PF-08032562 in People With Advanced or Metastatic Solid Tumors

  • START Midwest, LLC, Grand Rapids
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jul 22, 2026 · NCT07318805

A Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors

  • Karmanos Cancer Institute, Detroit
  • Karmanos Cancer Institute, Farmington Hills
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jul 22, 2026 · NCT05208762

A Study of Emiltatug Ledadotin (Emi-Le) in Participants With Solid Tumors

  • Henry Ford Health Hospital, Detroit
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT05377996

A Study of IDE034 in Adult Participants With Locally Advanced/Metastatic Solid Tumors Types

  • Karmanos Cancer Institute, Detroit
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 18, 2026 · NCT07503808

BAL0891 in Patients With Advanced Solid Tumors or Relapsed or Refractory Acute Myeloid Leukemia

  • University of Michigan, Ann Arbor
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 15, 2026 · NCT05768932

I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer

  • Herbert-Herman Cancer Center, Sparrow Hospital, Lansing
RecruitingPhase 2
Ages 18 and older · All sexes · Updated May 6, 2026 · NCT01042379

JAB-2485 Activity in Adult Patients With Advanced Solid Tumors

  • Henry Ford Health System, Detroit
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Jan 9, 2026 · NCT05490472

A Phase I/II Study of VLS-1488 in Subjects With Advanced Cancer

  • University of Michigan, Ann Arbor
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Nov 4, 2025 · NCT05902988

A Beta-only IL-2 ImmunoTherapY Study

  • Karmanos Cancer Institute, Detroit
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Jul 9, 2025 · NCT05086692

CtDNA Based MRD Testing for NAC Monitoring in TNBC

  • Trinity Health-Michigan, Ypsilanti
RecruitingObservational study
Ages 18 and older · Women · Updated Jan 7, 2025 · NCT06230185

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.