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Triple-Negative Breast Cancer clinical trials in Texas

59 studies for Triple-Negative Breast Cancer are looking for participants at sites in Texas.

Cities in Texas

Testing the Addition of an Individualized Vaccine to Durvalumab and Tremelimumab and Chemotherapy in Patients With Metastatic Triple Negative Breast Cancer

  • University of Texas Medical Branch, Galveston
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT03606967

A Phase 1 Study of PLN-101095 in Adults With Advanced or Metastatic Solid Tumors

  • NEXT Austin, Austin
  • START Center for Clinical Research, Fort Worth
  • University of Texas MD Anderson Cancer Center, Houston
  • and 2 more
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT06270706

A Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Triple-Negative Breast Cancer (MK-2870-011/TroFuse-011)

  • Texas Oncology - DFW ( Site 8007), Dallas
  • Texas Oncology - West Texas ( Site 8004), El Paso
  • Kelsey-Seybold Clinic - North Houston Campus ( Site 0096), Houston
  • and 2 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 10, 2026 · NCT06841354

A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)

  • Texas Oncology - DFW ( Site 8009), Dallas
  • UT Southwestern ( Site 0092), Dallas
  • Texas Oncology - Northeast Texas ( Site 8002), Flower Mound
  • and 6 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 10, 2026 · NCT06966700

A Study of IDE034 in Adult Participants With Locally Advanced/Metastatic Solid Tumors Types

  • NEXT Texas LLC - Austin, Austin
  • START Dallas Fort Worth, LLC, Fort Worth
  • MD Anderson, Houston
  • and 4 more
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 10, 2026 · NCT07503808

Phase 1 Study of a Self-amplifying RNA Vaccine (ITI-5000) in Stage 2-3 Triple Negative Breast Cancer

  • START San Antonio, San Antonio
RecruitingPhase 1
Ages 18 and older · Women · Updated Nov 9, 2026 · NCT07652242

A Study With NKT3964 for Adults With Advanced/Metastatic Solid Tumors

  • NEXT Oncology, Austin
  • UT Southwestern, Dallas
RecruitingPhase 1
Ages 19 and older · All sexes · Updated Nov 5, 2026 · NCT06586957

A Study With NKT5097 for Adults With Advanced/Metastatic Solid Tumors

  • University of Texas Southwestern Medical Center, Dallas
  • MD Anderson Cancer Center, Houston
  • South Texas Accelerated Research Therapeutics (START) San Antonio, San Antonio
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 5, 2026 · NCT07029399

A Study to Learn About the Study Medicine Called PF-08032562 in People With Advanced or Metastatic Solid Tumors

  • The University of Texas MD Anderson Cancer Center - Conroe, Conroe
  • The University of Texas - M.D. Anderson Cancer Center, Houston
  • The University of Texas, MD Anderson Cancer Center - West Houston, Houston
  • and 3 more
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 5, 2026 · NCT07318805

Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR (MK-2870-012)

  • Hendrick Medical Center ( Site 0117), Abilene
  • Harrington Cancer Center ( Site 0061), Amarillo
  • Texas Oncology - DFW ( Site 8000), Dallas
  • and 9 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 5, 2026 · NCT06393374

A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors

  • University of Texas MD Anderson Cancer Center, Houston
  • South Texas Accelerated Research Therapeutics (START), San Antonio
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT06465069

Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)

  • USOR Texas Oncology, Abilene
  • Texas Oncology - Central / South Texas, Austin
  • Mary Crowley Cancer Research, Dallas
  • and 3 more
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT05579366

A Study of Sofe-M in Participants With Selected Advanced Solid Tumors

  • The University of Texas - MD Anderson Cancer Center, Houston
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT06400472

Study of XB010 in Subjects With Solid Tumors

  • NEXT Austin, Austin
  • Baylor University Medical Center, Dallas
  • University of Texas MD Anderson Cancer Center, Houston
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 30, 2026 · NCT06545331

A Study of SHY-ONC6, a Novel Proteasome Inhibitor, in Adults With Advanced or Metastatic Solid Tumors

  • The University of Texas MD Anderson Cancer Center, Houston
  • NEXT Oncology, San Antonio
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 22, 2026 · NCT07705334

Intratumoral N17350 in Advanced Solid Tumors

  • The University of Texas MD Anderson Cancer Center, Houston
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 21, 2026 · NCT07339176

SMP-3124LP in Adults With Advanced Solid Tumors

  • MD Anderson Cancer Center, Houston
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 15, 2026 · NCT06526819

Study to Assess Adverse Events and Change in Disease Activity in Adult Participants With Select Advanced Solid Tumor Indications Receiving Intravenous (IV) ABBV-400

  • MD Anderson Cancer Center /ID# 255131, Houston
  • Univ Texas HSC San Antonio /ID# 257708, San Antonio
  • South Texas Accelerated Research Therapeutics /ID# 260404, San Antonio
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 14, 2026 · NCT06084481

First-in-Human Study of ATX-295, an Oral Inhibitor of KIF18A, as Monotherapy and in Combination With Anticancer Therapy in Patients With Advanced or Metastatic Solid Tumors, Including Ovarian Cancer

  • MD Anderson Cancer Center, Houston
  • NEXT Oncology, San Antonio
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 13, 2026 · NCT06799065

Neratinib in Combination With Ruxolitinib in Patients With mTNBC

  • Baylor University Medical Center, Baylor Charles A Sammons Cancer Center, Dallas
RecruitingEarly phase 1
Ages 18 and older · Women · Updated Oct 13, 2026 · NCT06008275

A Study to Evaluate ARV-6723 Alone and With Pembrolizumab in Participants With Advanced Solid Tumors

  • Clinical Trial Site, San Antonio
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 13, 2026 · NCT07749586

A Study to Investigate Safety of AZD6750 in Adult Participants With Select Advanced or Metastatic Solid Tumors

  • Research Site, Houston
  • Research Site, San Antonio
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 8, 2026 · NCT07115043

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

  • New Experimental Therapeutics - NEXT Oncology, Austin
  • Texas Oncology, Bedford
  • UT Southwest Simmons Cancer Center, Dallas
  • and 2 more
RecruitingPhase 1/2
Ages 12 and older · All sexes · Updated Oct 2, 2026 · NCT04585750

177Lu-BetaBart in Patients With Relapsed/Refractory, Locally Advanced Inoperable, or Metastatic Solid Tumors

  • MD Anderson Cancer Center, Houston
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT07189871

Study of AVZO-021 in Patients With Advanced Solid Tumors

  • Avenzo Therapeutics Recruiting Site, Dallas
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT05867251

Multicenter Trial for Eliminating Breast Cancer Surgery or Radiotherapy in Exceptional Responders to Neoadjuvant Systemic Therapy

  • M D Anderson Cancer Center, Houston
Recruiting
Ages 30 and older · Women · Updated Sep 25, 2026 · NCT02945579

A Study to Evaluate the Safety, Tolerability, Drug Levels, and Preliminary Efficacy of BMS-986507 Combinations in Adult Participants With Advanced Solid Tumors

  • NEXT Oncology - Irving, Irving
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT06618287

Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors

  • Oncology Consultants, P.A., Houston
  • University of Texas M.D. Anderson Cancer Center, Houston
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT05983432

Evolutionary Clinical Trial for Novel Biomarker-Driven Therapies

  • Baylor College of Medicine, Houston
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT07340541

A Study of [225Ac]Ac-AKY-1189 in Patients With Solid Tumors

  • MD Anderson Cancer Center, Houston
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07020117

First in Human Study of TUB-030 in Patients With Advanced Solid Tumors

  • NEXT Oncology Austin, Austin
  • NEXT Oncology - Dallas, Irving
  • NEXT Oncology - San Antonio, San Antonio
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 11, 2026 · NCT06657222

Evaluating Minimal Residual Disease (MRD) Through Longitudinal Circulating Tumor DNA (ctDNA) Profiling in Breast Malignancies

  • UT Health Houston, Houston
RecruitingObservational study
Ages 18 to 99 · All sexes · Updated Sep 3, 2026 · NCT07211178

A Phase 1 Study of NRM-823 in Participants With Locally Advanced or Metastatic Refractory Solid Tumors

  • Normunity Investigational Site, Dallas
  • Normunity Investigational Site, Houston
  • Normunity Investigational Site, San Antonio
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT07182149

A Study of BMS-986340 as Monotherapy and as Combination Therapy in Participants With Advanced Solid Tumors

  • Houston Methodist Hospital, Houston
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT04895709

Study to Assess GTAEXS617 in Participants With Advanced Solid Tumors

  • START San Antonio, San Antonio
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 13, 2026 · NCT05985655

A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01)

  • Texas Oncology - Central/South Texas, Austin
  • Texas Oncology - West Texas, El Paso
  • Texas Oncology - Northeast Texas, Flower Mound
  • and 1 more
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Aug 10, 2026 · NCT06926868

Phase I Study of [177Lu]Lu-NNS309 in Patients With Pancreatic, Lung, Breast and Colorectal Cancers

  • Uni Of TX MD Anderson Cancer Cntr, Houston
RecruitingPhase 1
Ages 18 to 100 · All sexes · Updated Jul 29, 2026 · NCT06562192

A Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors

  • University of Texas Southwestern Medical Center - Simmons Cancer Center, Dallas
  • UT Southwestern Medical Center - Redbird, Dallas
  • Univ. of TX Southwestern Medical Center - Zale Lipshy University Hospital, Dallas
  • and 8 more
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jul 22, 2026 · NCT05208762

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.