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Tuberous Sclerosis clinical trials recruiting in the U.S.

8 studies for Tuberous Sclerosis are recruiting participants at sites across the United States.

Tuberous sclerosis (TSC) is a rare genetic disease. It causes benign tumors in the brain and other organs. Learn about symptoms and what can help.

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Recently updated studies

Study of the Disease Process of Lymphangioleiomyomatosis

RecruitingObservational study
Ages 16 to 100 · All sexes · Updated Sep 28, 2026 · NCT00001465

Study of Skin Tumors in Tuberous Sclerosis

RecruitingObservational study
Ages 18 to 90 · All sexes · Updated Sep 28, 2026 · NCT00001975

Role of Genetic Factors in the Development of Lung Disease

RecruitingObservational studyHealthy volunteers welcome
Ages 2 to 90 · All sexes · Updated Sep 10, 2026 · NCT00001532

TSC Biosample Repository and Natural History Database

RecruitingObservational study
All ages · All sexes · Updated Jun 24, 2026 · NCT05676099

Familial Investigations of Childhood Cancer Predisposition

RecruitingObservational study
All ages · All sexes · Updated Jun 17, 2026 · NCT03050268

Tuberous Sclerosis Complex and Lymphangioleiomyomatosis Pregnancy Registry (TSC-LAM Registry)

RecruitingObservational study
All ages · Women · Updated Jan 23, 2026 · NCT06160310

Stopping TSC Onset and Progression 2B: Sirolimus TSC Epilepsy Prevention Study

RecruitingPhase 2
1 Day – 6 Months · All sexes · Updated Jan 22, 2026 · NCT05104983

ESIS in Pediatric DRE

RecruitingObservational study
Ages 1 to 30 · All sexes · Updated Dec 23, 2025 · NCT05469373

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.