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Viral Infections clinical trials recruiting in the U.S.

31 studies for Viral Infections are recruiting participants at sites across the United States.

Viruses cause familiar infections such as the common cold, but they also cause severe illnesses. Learn more about viral infections and their symptoms.

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Recently updated studies

A Study of COVID-19 Vaccine(s) in Children and Adults

RecruitingPhase 3Healthy volunteers welcome
Ages 5 and older · All sexes · Updated Sep 28, 2026 · NCT07798648

Specimen Collections From Participants With HIV Infection, KSHV Infection, Viral-Related Pre-malignant Lesions and Cancer

RecruitingObservational study
Ages 18 to 120 · All sexes · Updated Sep 28, 2026 · NCT00006518

The Natural History of Severe Viral Infections and Characterization of Immune Defects in Patients Without Known Immunocompromise

RecruitingObservational study
Ages 2 to 100 · All sexes · Updated Sep 28, 2026 · NCT01011712

A Study to Learn About the Study Medicine Ibuzatrelvir in Adults With COVID-19 Who Are Severely Immunocompromised

RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07013474

Phase 1 Challenge Study Using rDEN2delta30-7169 to Evaluate Host-Pathogen Interactions in Primary, Homotypic, and Heterotypic Dengue Virus Infection

RecruitingPhase 1Healthy volunteers welcome
Ages 18 to 50 · All sexes · Updated Sep 25, 2026 · NCT07706686

Study of AHB-137 in Chronic Hepatitis B (CHB) Participants in North America and Europe Regions

RecruitingPhase 2
Ages 18 to 65 · All sexes · Updated Sep 24, 2026 · NCT07654283

Viral Infections in Healthy and Immunocompromised Hosts

RecruitingObservational studyHealthy volunteers welcome
6 Months – 120 Years · All sexes · Updated Sep 14, 2026 · NCT01306084

Acute Infection in Mitochondrial Disease: Metabolism, Infection and Immunity

RecruitingObservational studyHealthy volunteers welcome
2 Months – 115 Years · All sexes · Updated Sep 10, 2026 · NCT04419870

HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors

RecruitingPhase 1
36 Months – 22 Years · All sexes · Updated Sep 4, 2026 · NCT03911388

Donor-Derived Viral Specific T-cells (VSTs)

RecruitingPhase 1/2
4 Weeks · All sexes · Updated Sep 4, 2026 · NCT02048332

Third Party Viral Specific T-cells (VSTs)

RecruitingPhase 2
2 Days · All sexes · Updated Sep 4, 2026 · NCT02532452

Efficacy and Safety of Tozorakimab in Patients Hospitalised for Viral Lung Infection Requiring Supplemental Oxygen

RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 28, 2026 · NCT05624450

A Phase 1/2A, Randomized Study of a T Follicular Helper (TFH)-Targeting Genetic Vaccine Strategy Designed to Induce Broad, Durable Immune Responses

RecruitingPhase 1/2Healthy volunteers welcome
Ages 40 to 64 · All sexes · Updated Aug 18, 2026 · NCT06810934

A Study to Learn About a COVID-19 Vaccine in Healthy Adults 18 Through 64 Years of Age

RecruitingPhase 4Healthy volunteers welcome
Ages 18 to 64 · All sexes · Updated Aug 7, 2026 · NCT07730450

Genetic Studies of Chronic Active Epstein-Barr Disease

RecruitingObservational study
Ages 1 to 120 · All sexes · Updated Jul 28, 2026 · NCT00032513

TETRAVI Multivirus CTL for Treatment of EBV, CMV, Adenovirus, and BK Infections Post Allogeneic SCT.

RecruitingPhase 1
All ages · All sexes · Updated Jun 11, 2026 · NCT04013802

Treatment of Refractory BK Infections With Related Donor BK Specific Cytotoxic T-cells (CTLs)

RecruitingPhase 1/2
1 Month – 79 Years · All sexes · Updated Apr 15, 2026 · NCT04197596

A Study to Investigate the Immunogenicity and Safety of mRNA COVID-19 Variant-containing Vaccine Formulations

RecruitingPhase 4Healthy volunteers welcome
6 Months · All sexes · Updated Mar 27, 2026 · NCT06585241

Microbial Cell-free Metagenomic Sequencing for Suspected Infections in Adult Immunocompromised Outpatients

Recruiting
Ages 18 and older · All sexes · Updated Jan 30, 2026 · NCT07110636

Adoptive T Lymphocyte Administration for Chronic Norovirus Treatment in Immunocompromised Hosts

RecruitingPhase 1
3 Months – 80 Years · All sexes · Updated Jan 26, 2026 · NCT04691622

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.