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Lung Cancer clinical trials in Grand Rapids, MI

14 studies for Lung Cancer are looking for participants at sites in and around Grand Rapids (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

RecruitingPhase 3
  • Corewell Health Grand Rapids Hospitals - Butterworth Hospital, Grand Rapids
  • Trinity Health Grand Rapids Hospital, Grand Rapids
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT04267848

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Corewell Health Grand Rapids Hospitals - Butterworth Hospital, Grand Rapids
  • Corewell Health Grand Rapids Hospitals - Helen DeVos Children's Hospital, Grand Rapids
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

Chemotherapy Combined With Immunotherapy Versus Immunotherapy Alone for Older Adults With Stage IIIB-IV Lung Cancer, The ACHIEVE Trial

RecruitingPhase 3
  • Corewell Health Grand Rapids Hospitals - Butterworth Hospital, Grand Rapids
Ages 70 and older · All sexes · Updated Oct 1, 2026 · NCT06096844

Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial

RecruitingPhase 3
  • Corewell Health Grand Rapids Hospitals - Butterworth Hospital, Grand Rapids
  • Trinity Health Grand Rapids Hospital, Grand Rapids
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06498635

This is a Study to Learn About How the Combination of the Study Medicines Sigvotatug Vedotin Plus Pembrolizumab Works in People With Non-small Cell Lung Cancer With High Levels of PD-L1.

RecruitingPhase 3
  • Corewell Health - Butterworth Hospital, Grand Rapids
  • Corewell Health - Lemmen Holton Cancer Pavilion, Grand Rapids
  • Corewell Health - Research Specimen Processing Area, Grand Rapids
  • and 2 more
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06758401

Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

RecruitingPhase 1/2
  • START Midwest, Grand Rapids
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06128551

Study of RMC-5127 in Patients With Advanced KRAS G12V-Mutant Solid Tumors

RecruitingPhase 1
  • START Midwest, Grand Rapids
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07349537

Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies

RecruitingPhase 1/2
  • South Texas Accelerated Research Therapeutics (START) Midwest, Grand Rapids
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT05786924

A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

RecruitingPhase 3
  • The Cancer & Hematology Centers, Grand Rapids
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06119581

A Study of Sofe-M in Participants With Selected Advanced Solid Tumors

RecruitingPhase 1
  • South Texas Accelerated Research Therapeutics (START) Midwest, Grand Rapids
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT06400472

Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer

RecruitingPhase 3
  • Trinity Health Grand Rapids Hospital, Grand Rapids
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT05624996

Study Evaluating the Safety and Efficacy of HWK-007, a PTK7-directed Antibody Drug Conjugate in Participants With Advanced Solid Tumors

RecruitingPhase 1
  • START - Midwest, Grand Rapids
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT07444814

A Study of ZW251 in Participants With Advanced Solid Tumors

RecruitingPhase 1
  • START Midwest, Grand Rapids
Ages 18 and older · All sexes · Updated May 7, 2026 · NCT07164313

LOTUS-CC: An Observational Research Study to Uncover Subtypes of Cancer Cachexia

RecruitingObservational study
  • Corewell Health Grand Rapids Hospitals - Butterworth Hospital, Grand Rapids
  • Trinity Health Grand Rapids Hospital, Grand Rapids
Ages 18 and older · All sexes · Updated Jan 9, 2026 · NCT06073431

About Lung Cancer

Lung cancer forms in tissues of the lung, usually in the cells that line the air passages. It is the leading cause of cancer death in both men and women.

More about Lung Cancer on MedlinePlus

Lung Cancer trials in other cities

Other studies in Grand Rapids

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.