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Salivary Gland Cancer clinical trials recruiting in the U.S.

15 studies for Salivary Gland Cancer are recruiting participants at sites across the United States.

Salivary glands empty saliva into your mouth. Salivary gland cancer is a rare type of head and neck cancer. Learn about the associated symptoms.

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Recently updated studies

DESTINY-PANTUMOUR04

RecruitingObservational study
Ages 18 to 130 · All sexes · Updated Sep 25, 2026 · NCT07124000

Phase II Trial of Sacituzumab Govitecan in Recurrent and/or Metastatic Secretory Gland Cancers

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jul 16, 2026 · NCT05884320

A Phase 2 Study of Zanidatamab in Patients With HER2-expressing Tumors

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jul 10, 2026 · NCT06695845

Integrated Cancer Repository for Cancer Research

RecruitingObservational studyHealthy volunteers welcome
Ages 19 to 110 · All sexes · Updated Jun 29, 2026 · NCT02012699

Oropharynx (OPX) Biomarker Trial

RecruitingObservational study
Ages 18 and older · All sexes · Updated Apr 22, 2026 · NCT06356272

Post-op T-DM1 in HER-2+ Salivary Gland Carcinomas

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT04620187

Binary Oncolytic Adenovirus in Combination With HER2-Specific Autologous CAR VST, Advanced HER2 Positive Solid Tumors

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Feb 6, 2026 · NCT03740256

Drug Screening Using Novel IMD in Salivary and Head and Neck Cancers

RecruitingEarly phase 1
Ages 18 and older · All sexes · Updated Jan 26, 2026 · NCT05553782

VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma

RecruitingPhase 1/2
Ages 18 to 80 · All sexes · Updated Dec 11, 2025 · NCT03556228

Tissue Sample Collection From Patients With Head and Neck Cancer and From Healthy Participants

RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Oct 28, 2025 · NCT00898638

A Study to Evaluate TROP2 ADC LCB84 Single Agent and in Combination With an Anti-PD-1 Ab in Advanced Solid Tumors

RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 24, 2025 · NCT05941507

Physiologic MR Imaging of Salivary Gland Tumors

Recruiting
Ages 18 and older · All sexes · Updated Sep 9, 2025 · NCT04452162

A Phase 2 Trial of Ivonescimab for Patients With Advanced, Metastatic Salivary Gland Cancers

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jul 29, 2025 · NCT06805617

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.