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Urothelial (Transitional Cell) Carcinoma clinical trials in Pennsylvania

15 studies for Urothelial (Transitional Cell) Carcinoma are looking for participants at sites in Pennsylvania.

Cities in Pennsylvania

Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors

  • Exelixis Clinical Site #104, Hershey
  • Exelixis Clinical Site #98, Philadelphia
  • Exelixis Clinical Site #32, Pittsburgh
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT05176483

A Study Comparing the Combination of Pembrolizumab and Sacituzumab Govitecan-hziy Versus Standard of Care in the Treatment of Advanced Urothelial Cancer

  • Geisinger Medical Center, Danville
  • Geisinger Cancer Center Dickson City, Dickson City
  • UPMC Hillman Cancer Center Erie, Erie
  • and 22 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06524544

Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

  • Lehigh Valley Hospital-Cedar Crest, Allentown
  • Lehigh Valley Hospital - Muhlenberg, Bethlehem
  • Pocono Medical Center, East Stroudsburg
  • and 8 more
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT03866382

A Substudy of Investigational Agents in Programmed Cell Death-1/Ligand 1 (PD-1/L1) Refractory Locally Advanced or Metastatic Urothelial Carcinoma (mUC) (MK-3475-04A)

  • UPMC Hillman Cancer Center ( Site 1014), Pittsburgh
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT05562830

A Study of IDE892 as Monotherapy and Combination in MTAP-deleted Advanced Solid Tumors

  • Sidney Kimmel Comprehensive Cancer Center Thomas Jefferson University, Philadelphia
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07277413

A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract

  • Lancaster General Hospital - Ann B Barshinger Cancer Institute, Lancaster
  • AHN Allegheny General Hospital, Pittsburgh
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07218380

Gemcitabine and Carboplatin After Progression on Enfortumab Vedotin and Pembrolizumab in Advanced/Metastatic Urothelial Carcinoma

  • Fox Chase Cancer Center, Philadelphia
  • Temple University Hospital at Broad Street, Philadelphia
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07043972

A Phase 3 Single-arm Study of UGN-104 for the Treatment of Low-grade Upper Tract Urothelial Cancer

  • Penn State Milton S Hershey Medical Center, Hershey
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT06774131

Study of DCC-2812 in Participants With Advanced Genitourinary Cancers

  • Fox Chase Cancer Center, Philadelphia
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT06966024

Study of Neoadjuvant Enfortumab Vedotin and Pembrolizumab in Upper Tract Urothelial Cancer

  • Fox Chase Cancer Center, Philadelphia
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jul 16, 2026 · NCT06356155

Study to Assess the Impact of the Urine Test Cxbladder Triage Plus on the Number of Cystoscopies Performed on Patients With Invisible Blood in Their Urine.

  • Penn State Medical Center, Urology Research, Hershey
Recruiting
Ages 18 to 88 · All sexes · Updated Jul 2, 2026 · NCT06394869

Pembrolizumab Maintenance After Enfortumab Vedotin (EV)/Pembro Induction in Front-Line Metastatic Urothelial Carcinoma

  • Fox Chase Cancer Center - Philadelphia, Philadelphia
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Feb 19, 2026 · NCT07221942

Clinical Trial to Evaluate Post-Operative Outcomes of Ureteral Stent vs Ureteral Stent Free Radical Cystectomy

  • Thomas Jefferson University Hospital, Philadelphia
  • Jefferson Einstein Philadelphia Hospital, Philadelphia
Recruiting
Ages 18 to 85 · All sexes · Updated Feb 17, 2026 · NCT07234968

Increasing Pre-Surgical Identification of Muscle Invasive Tumor Evaluations Prior to Planned Cystectomy (INSITE)

  • Fox Chase Cancer Center, Philadelphia
RecruitingObservational study
Ages 18 and older · All sexes · Updated Oct 31, 2025 · NCT06396533

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

  • Massive Bio SYNERGY-AI site, Philadelphia
RecruitingObservational study
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.