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Hemophagocytic Lymphohistiocytosis clinical trials recruiting in the U.S.
7 studies for Hemophagocytic Lymphohistiocytosis are recruiting participants at sites across the United States.
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Recently updated studies
Ruxolitinib With De-Intensified HLH-94 for the Treatment of Hemophagocytic Lymphohistiocytosis (HLH)
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT06160791Hemophagocytic Lymphohistiocytosis (HLH) Evaluation and Research of Clinical, ImmUnoLogic and TranscriptomE Study
RecruitingObservational study
Ages 18 to 120 · All sexes · Updated Sep 10, 2026 · NCT06339177INTO-HLH: A Disease Registry for Patients With Hemophagocytic Lymphohistiocytosis (HLH)
RecruitingObservational study
All ages · All sexes · Updated Feb 24, 2026 · NCT05277272Describing Treatment Outcomes and Responses in Lymphoma-associated Hemophagocytic Lymphohistiocytosis
RecruitingObservational study
All ages · All sexes · Updated Jan 22, 2026 · NCT05898477Data Collection Study of Patients With Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT With RIC
RecruitingObservational study
2 Months – 60 Years · All sexes · Updated Jan 13, 2026 · NCT04528355Reduced Intensity Conditioning for Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT
RecruitingPhase 2
2 Months – 55 Years · All sexes · Updated Dec 15, 2025 · NCT01962415Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
RecruitingObservational study
All ages · All sexes · Updated May 29, 2025 · NCT01793168From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.