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Kidney Cancer (Renal Cell Carcinoma) clinical trials in Florida

31 studies for Kidney Cancer (Renal Cell Carcinoma) are looking for participants at sites in Florida.

Cities in Florida

A Phase 1 Study of AB521 Monotherapy and Combination Therapies in Renal Cell Carcinoma and Other Solid Tumors

  • Research Site, Miami
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT05536141

Open-Label Phase 1/2 Study of NEO-811 in Subjects With Locally Advanced or Metastatic Non-Resectable Clear Cell Renal Cell Carcinoma

  • NEO-811 Florida Site, Miami
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT07300241

Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program

  • Mayo Clinic in Florida, Jacksonville
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06265285

A Phase 1 Study of the Safety and Tolerability of CTX-10726

  • Mayo Clinic Florida, Jacksonville
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07419841

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

  • Mount Sinai Comprehensive Cancer Center at Aventura, Aventura
  • Schulze Family Foundation Cancer Clinic - Bonita Health Center, Bonita Springs
  • Morton Plant Hospital, Clearwater
  • and 11 more
RecruitingObservational studyHealthy volunteers welcome
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors

  • Exelixis Clinical Site #48, Celebration
  • Exelixis Clinical Site #11, Gainesville
  • Exelixis Clinical Site #78, Jacksonville
  • and 2 more
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT05176483

Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

  • Holy Cross Hospital, Fort Lauderdale
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT03866382

DESTINY-PANTUMOUR04

  • Research Site, Coral Springs
  • Research Site, St. Petersburg
  • Research Site, West Palm Beach
RecruitingObservational study
Ages 18 to 130 · All sexes · Updated Sep 25, 2026 · NCT07124000

Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing

  • Mayo Clinic Jacksonville, Jacksonville
  • Moffitt Cancer Center, Tampa
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT04981119

Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis

  • MDR Core Network, Boynton Beach
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT06047379

A Study to Evaluate the Safety, Tolerability, and Efficacy of Pumitamig Alone or in Combination With Other Agents in Participants With Advanced Renal Cell Carcinoma (RCC) (ROSETTA RCC-208)

  • Local Institution - 0177, Miami
  • Local Institution - 0126, Orlando
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07293351

Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rα Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer

  • Sylvester Comprehensive Cancer Center - Miami, Miami
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT05267626

Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, SAMURAI Trial

  • Mount Sinai Comprehensive Cancer Center at Aventura, Aventura
  • Memorial Regional Hospital/Joe DiMaggio Children's Hospital, Hollywood
  • Mayo Clinic in Florida, Jacksonville
  • and 3 more
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT05327686

Symbiotic-GU-08: A Study to Learn About the Medicine Called PF-08634404 Dosed Alone and in Combination With Other Anticancer Therapies in Adults With Locally Advanced or Metastatic Renal Cell Cancer

  • Mayo Clinic Pharmacy, Jacksonville
  • Orlando Health Ambulatory Care Center, Orlando
  • Orlando Health Cancer Institute, Orlando
  • and 1 more
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07227415

ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation

  • Memorial Healthcare System, Hollywood
  • The Oncology Institute of Hope & Innovation, Lakeland
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT05059444

Testing the Addition of the Anti-Cancer Drug Tivozanib to Immunotherapy (Pembrolizumab) After Surgery to Remove All Known Sites of Kidney Cancer

  • UF Health Cancer Institute - Gainesville, Gainesville
  • Miami Cancer Institute, Miami
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT06661720

Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors

  • Mayo Clinic in Florida, Jacksonville
RecruitingPhase 1/2
Ages 16 and older · All sexes · Updated Aug 20, 2026 · NCT05269381

Study of XmAb®819 in Subjects With Advanced Clear Cell Renal Cell Carcinoma

  • Xencor Investigative Site, Jacksonville
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 3, 2026 · NCT05433142

Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)

  • Clermont Oncology Center, Clermont
  • Mid Florida Hematology and Oncology Center, Orange City
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Jul 29, 2026 · NCT04198766

A Trial to Find Out if REGN5678 (Nezastomig) is Safe and How Well it Works Alone or in Combination With Cemiplimab for Adult Participants With Metastatic Castration-Resistant Prostate Cancer and Other Tumors

  • Mayo Clinic Jacksonville, Jacksonville
  • Moffitt Cancer Center - McKinley Drive, Tampa
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Jul 9, 2026 · NCT03972657

KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors

  • AdventHealth Celebration, Celebration
  • Mayo Clinic Comprehensive Cancer Center, Jacksonville
  • Florida Cancer Specialists, Sarasota
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 8, 2026 · NCT06026410

A Study of VET3-TGI in Patients With Solid Tumors

  • University of Miami, Miami
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Apr 7, 2026 · NCT06444815

Immune Checkpoint Inhibitor Response in Solid Tumors Using a Live Tumor Diagnostic Platform

  • Mayo Clinic in Florida, Jacksonville
RecruitingObservational study
Ages 18 and older · All sexes · Updated Mar 12, 2026 · NCT06349642

A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression

  • Mayo Clinic, Jacksonville
  • Moffitt Cancer Center, Tampa
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 9, 2025 · NCT06682793

Comparing the Outcome of Immunotherapy-Based Drug Combination Therapy With or Without Surgery to Remove the Kidney in Metastatic Kidney Cancer, the PROBE Trial

  • AdventHealth Altamonte, Altamonte Springs
  • AdventHealth Celebration, Celebration
  • AdventHealth Kissimmee, Kissimmee
  • and 5 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 9, 2025 · NCT04510597

A Beta-only IL-2 ImmunoTherapY Study

  • Boca Raton Regional Hospital, Boca Raton
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Jul 9, 2025 · NCT05086692

A Study of IBI363 in Subjects with Advanced Solid Malignancies

  • Ocala Oncology Center, Ocala
  • BRCR Medical Center, Plantation
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Dec 19, 2024 · NCT06281678

Phase 1a and Phase 2 Study for Safety, Preliminary Efficacy, PK and PD of ST-067

  • Moffitt Cancer Center, Tampa
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Nov 15, 2024 · NCT04787042

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.