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Mantle Cell Lymphoma clinical trials in California

29 studies for Mantle Cell Lymphoma are looking for participants at sites in California.

Cities in California

Testing Continuous Versus Intermittent Treatment With the Study Drug Zanubrutinib for Older Patients With Previously Untreated Mantle Cell Lymphoma

  • Tower Cancer Research Foundation, Beverly Hills
  • Cedars-Sinai Medical Center, Los Angeles
RecruitingPhase 3
Ages 60 and older · All sexes · Updated Oct 2, 2026 · NCT05976763

Glofitamab With Pirtobrutinib for Relapsed or Refractory Mantle Cell Lymphoma

  • University of California, Davis, Davis
  • University of California, Los Angeles, Los Angeles
  • University of California, San Diego, San Diego
  • and 1 more
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06252675

A Study to Evaluate Safety, PK, PD and Efficacy of AZD5492, a T Cell-engaging Antibody Targeting CD20 in Subjects With R/R B-Cell Malignancies.

  • Research Site, La Jolla
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT06542250

A Study to Investigate the Efficacy and Safety of Sonrotoclax Plus Zanubrutinib Compared With Placebo Plus Zanubrutinib in Adults With Relapsed/Refractory Mantle Cell Lymphoma (CELESTIAL-RRMCL)

  • Ucsf Fresno, Fresno
  • Kaiser Permanente Southern California, Irvine
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT06742996

A Dose-Escalation and Expansion Study of Tacabrutideg (BGB-16673) in Participants With B-Cell Malignancies

  • University of California San Diego (Ucsd) Moores Cancer Center, La Jolla
  • Stanford Medicine, Palo Alto
  • UCLA Santa Monica Cancer Care, Santa Monica
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT05006716

Phase 2 Open Label Randomized Study of Pirtobrutinib and Brexucabtagene Autoleucel in R/R MCL

  • Stanford Cancer Center, Stanford
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT06553872

A Study of LY4152199 in Participants With Previously Treated B-cell Malignancies (BAF_FRontier-1 )

  • City of Hope, Duarte
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07101328

Testing the Anti-cancer Drug, Glofitamab, in Patients With Mantle Cell Lymphoma (A Type of Blood Cancer) Whose Disease Returned After CAR-T Cell Therapy

  • City of Hope Comprehensive Cancer Center, Duarte
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT07003295

A Study of ARC-02 in B-cell NHL

  • Start Cala, Los Angeles
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 26, 2026 · NCT07691606

AutologousCD22 Chimeric Antigen Receptor (CAR)T Cells in w/Recurrent/Refractory B Cell Lymphomas

  • Stanford University, Palo Alto
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 12, 2026 · NCT06340737

Gene Therapy for CD19-Positive Hematologic Malignancies (SENTRY-CD19)

  • City of Hope, Duarte
  • Valkyrie Clinical Trials, Los Angeles
RecruitingPhase 1/2
Ages 13 to 90 · All sexes · Updated Aug 6, 2026 · NCT06533579

Pacritinib in Combination With a BTK Inhibitor for the Treatment of Patients With Relapsed or Refractory Mantle Cell Lymphoma

  • City of Hope Medical Center, Duarte
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT06675123

A Study of APG-3288 in Relapsed/Refractory Blood Cancers

  • START Los Angele, Los Angeles
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jul 30, 2026 · NCT07424833

This is a Phase 1 Study to Evaluate the Safety of LTZ-301 in Patients With Non-Hodgkin Lymphoma

  • City of Hope, Duarte
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jul 24, 2026 · NCT07121946

DALY II USA/ MB-CART2019.1 for DLBCL

  • UC San Diego Health, La Jolla
  • Stanford University, Stanford
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jul 13, 2026 · NCT04792489

A Study of NX-5948 in Adults With Relapsed/Refractory B-cell Malignancies

  • City of Hope, Duarte
  • University of California, San Francisco, San Francisco
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jul 2, 2026 · NCT05131022

Anti-CD19 Chimeric Antigen Receptor T Cells for Treatment of Relapsed or Refractory Non-Hodgkin Lymphoma

  • University of California, San Francisco, San Francisco
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 22, 2026 · NCT04545762

Venetoclax, Lenalidomide and Rituximab in Patients With Previously Untreated Mantle Cell Lymphoma

  • City of Hope Medical center, Duarte
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Apr 22, 2026 · NCT03523975

Zanubrutinib in Combination With Sonrotoclax for the Treatment of Underrepresented Ethnic and Racial Minorities With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma

  • City of Hope Medical Center, Duarte
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Apr 20, 2026 · NCT06859008

The OPAL Study: AVM0703 for Treatment of Lymphoid Malignancies

  • City of Hope, Duarte
  • Los Angeles Cancer Network, Los Angeles
  • UCLA Medical Center of Hematology/Oncology, Los Angeles
  • and 1 more
RecruitingPhase 1/2
Ages 12 to 95 · All sexes · Updated Apr 15, 2026 · NCT04329728

A Study of NX-2127 in Adults With Relapsed/Refractory B-cell Malignancies

  • City of Hope, Duarte
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Mar 20, 2026 · NCT04830137

Nemtabrutinib With Rituximab for the Treatment of Patients With Mantle Cell Lymphoma

  • City of Hope Medical Center, Duarte
  • City of Hope at Irvine Lennar, Irvine
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Mar 13, 2026 · NCT06572618

Acalabrutinib, Obinutuzumab, and Glofitamab for the Treatment of Relapsed or Refractory Mantle Cell Lymphoma

  • City of Hope Medical Center, Duarte
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jan 5, 2026 · NCT06054776

AS-1763 in Patients With Previously Treated CLL/SLL or Non-Hodgkin Lymphoma

  • UC Irvine Health, Orange
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Dec 10, 2025 · NCT05602363

BAFFR-targeting CAR T Cells for Patients With Relapsed or Refractory B-NHL

  • City of Hope Medical Center, Duarte
  • Stanford University, Stanford
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 20, 2025 · NCT05370430

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

  • Massive Bio SYNERGY-AI site, Duarte
  • Massive Bio SYNERGY-AI site, Irvine
  • Massive Bio SYNERGY-AI site, La Jolla
  • and 3 more
RecruitingObservational study
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

Optimizing ctDNA-based MRD Assessment in DLBCL, MCL, and FL Patients Undergoing CAR Therapy

  • Stanford Cancer Center, Palo Alto
RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 22, 2024 · NCT05255354

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.