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Triple-Negative Breast Cancer clinical trials in New York City, NY

31 studies for Triple-Negative Breast Cancer are looking for participants at sites in and around New York City (within about 30 miles). Open a study to see who can join and how to contact the study team.

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A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors

RecruitingPhase 1
  • NYU Langone Medical Center - Perlmutter Cancer Center (NYU Cancer Institute), New York
  • NYU Langone Medical Center - Perlmutter Cancer Center (NYU Cancer Institute), New York
  • Icahn School of Medicine at Mount Sinai, New York
  • and 2 more
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06465069

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

RecruitingPhase 1/2
  • Columbia University Medical Center, New York
  • Memorial Sloan Kettering, New York
Ages 12 and older · All sexes · Updated Oct 2, 2026 · NCT04585750

Testing the Addition of Anti-Cancer Drug, ZEN003694 (ZEN-3694) and PD-1 Inhibitor (Pembrolizumab), to Standard Chemotherapy (Nab-Paclitaxel) Treatment in Patients With Advanced Triple-Negative Breast Cancer

RecruitingPhase 1
  • Laura and Isaac Perlmutter Cancer Center at NYU Langone, New York
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT05422794

Study of AVZO-021 in Patients With Advanced Solid Tumors

RecruitingPhase 1/2
  • Avenzo Therapeutics Recruiting Site, New York
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT05867251

Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing

RecruitingObservational study
  • NYU Langone Medical Center, New York
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT04981119

A Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Triple-Negative Breast Cancer (MK-2870-011/TroFuse-011)

RecruitingPhase 3
  • Laura and Isaac Perlmutter Cancer Center ( Site 0003), New York
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06841354

Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR (MK-2870-012)

RecruitingPhase 3
  • The Blavatnik Family- Chelsea Medical Center at Mount Sinai ( Site 0135), New York
  • Icahn School of Medicine at Mount Sinai ( Site 0123), New York
  • Memorial Sloan Kettering Cancer Center ( Site 0067), New York
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06393374

Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors

RecruitingPhase 1
  • Memorial Sloan Kettering Cancer Center Head Neck Services, New York
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT05983432

A Study of [225Ac]Ac-AKY-1189 in Patients With Solid Tumors

RecruitingPhase 1
  • Icahn School of Medicine at Mt. Sinai, New York
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07020117

A Study of Pembrolizumab and Ablation (Cryoablation or Histotripsy) in People With Breast Cancer

RecruitingPhase 1
  • Memorial Sloan Kettering Cancer Center (All protocol activites), New York
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT06246968

First in Human Study of TUB-030 in Patients With Advanced Solid Tumors

RecruitingPhase 1/2
  • Mount Sinai, New York
Ages 18 and older · All sexes · Updated Sep 11, 2026 · NCT06657222

A Study of SDX-7320 in Combination With Eribulin for People With Breast Cancer

RecruitingPhase 2
  • Memorial Sloan Kettering Cancer Center (All Protocol Activities), New York
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT05570253

Testing the Addition of an Individualized Vaccine to Durvalumab and Tremelimumab and Chemotherapy in Patients With Metastatic Triple Negative Breast Cancer

RecruitingPhase 2
  • NYP/Weill Cornell Medical Center, New York
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT03606967

A Study of Sofe-M in Participants With Selected Advanced Solid Tumors

RecruitingPhase 1
  • New York University (NYU) Clinical Cancer Center, New York
  • David H. Koch Center for Cancer Care at Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT06400472

A Study of Cyclophosphamide, Methotrexate, Fluorouracil (CMF) for People With Breast Cancer

RecruitingPhase 2
  • Memorial Sloan-Kettering Cancer Center (All Protocol Activities), New York
Ages 70 and older · All sexes · Updated Aug 17, 2026 · NCT07768436

Study to Assess GTAEXS617 in Participants With Advanced Solid Tumors

RecruitingPhase 1/2
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Aug 13, 2026 · NCT05985655

A Study to Learn About the Study Medicine Called PF-08032562 in People With Advanced or Metastatic Solid Tumors

RecruitingPhase 1
  • Memorial Sloan Kettering Cancer Center - David H. Koch Center for Cancer Care (74th Street)., New York
  • Memorial Sloan Kettering Cancer Center 53rd street., New York
  • Memorial Sloan Kettering Cancer Center - Main Campus, New York
Ages 18 and older · All sexes · Updated Jul 22, 2026 · NCT07318805

A Study of Emiltatug Ledadotin (Emi-Le) in Participants With Solid Tumors

RecruitingPhase 1/2
  • New York University Langone Health, New York
  • ICHAN School of Medicine at Mount Sinai, New York
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT05377996

A Study of LY4175408 in Participants With Advanced Cancer

RecruitingPhase 1
  • Columbia University, New York
  • David H. Koch Center for Cancer Care at Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Jun 23, 2026 · NCT07046923

BAL0891 in Patients With Advanced Solid Tumors or Relapsed or Refractory Acute Myeloid Leukemia

RecruitingPhase 1
  • New York Medicine-New York-Presbyterian Hospital, New York
  • Montefiore Medical Center - Montefiore Hospital, New York
Ages 18 and older · All sexes · Updated Jun 15, 2026 · NCT05768932

Neoadjuvant Dupilumab, Pembrolizumab, Paclitaxel, and Carboplatin in Locally Advanced Triple Negative Breast Cancer

RecruitingEarly phase 1
  • Mount Sinai Health System, New York
Ages 18 and older · All sexes · Updated May 14, 2026 · NCT06637306

I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer

RecruitingPhase 2
  • Laura and Isaac Perlmutter Cancer Center / NYU Langone Health, New York
  • Columbia University Medical Center, New York
Ages 18 and older · All sexes · Updated May 6, 2026 · NCT01042379

A Study of Tetrathiomolybdate (TM) Plus Capecitabine

RecruitingPhase 1/2
  • NYU Langone perimutter Cancer Center, New York
Ages 18 to 80 · All sexes · Updated Apr 20, 2026 · NCT06134375

A Dose Randomization Study of Bulumtatug Fuvedotin in TNBC Patients Previously Treated With ADCs

RecruitingPhase 1
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Mar 17, 2026 · NCT06908928

Investigating the Effectiveness of Stereotactic Body Radiotherapy (SBRT) in Addition to Standard of Care Treatment for Cancer That Has Spread Beyond the Original Site of Disease

RecruitingPhase 2
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Feb 27, 2026 · NCT03808337

A Study of Radiation Therapy With Pembrolizumab and Olaparib or Other Radiosensitizers in Women Who Have Triple-Negative or Hormone-Receptor Positive/Her2 Negative Breast Cancer

RecruitingPhase 2
  • Memorial Sloan Kettering Cancer Center (All Protocol Activities), New York
Ages 18 and older · Women · Updated Feb 17, 2026 · NCT04683679

A Phase I/II Study of VLS-1488 in Subjects With Advanced Cancer

RecruitingPhase 1/2
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Nov 4, 2025 · NCT05902988

Triple-Negative Breast Cancer trials in other cities

Other studies in New York City

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.