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Breast Cancer clinical trials in Wisconsin

44 studies for Breast Cancer are looking for participants at sites in Wisconsin.

Cities in Wisconsin

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

  • University of Wisconsin Carbone Cancer Center, Madison
RecruitingPhase 1/2
Ages 12 and older · All sexes · Updated Oct 2, 2026 · NCT04585750

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

  • Aspirus Cancer Care-Antigo-Volm Cancer Center, Antigo
  • ThedaCare Regional Cancer Center, Appleton
  • ThedaCare Regional Medical Center - Appleton, Appleton
  • and 50 more
RecruitingObservational studyHealthy volunteers welcome
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

A Phase 2 Neoadjuvant Study of Zanidatamab in Combination With Chemotherapy in Participants With HER2-positive Breast Cancer

  • University of Wisconsin, Madison
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT07102381

Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors

  • Wisconsin Institute for Medical Research, Madison
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06625775

A Study of NT-175 in Adult Participants With Advanced Malignancies That Are Positive for HLA-A*02:01 and the TP53 R175H Mutation

  • Research Site, Milwaukee
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT05877599

A Clinical Study of Patritumab Deruxtecan to Treat Breast Cancer (MK-1022-016)

  • Circuit Clinical/SSM Health Dean Medical Group ( Site 0039), Madison
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07060807

A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)

  • University of Wisconsin-Madison ( Site 0024), Madison
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06966700

A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)

  • University Hospital and UW Health Clinics-Carbone Cancer Center ( Site 0040), Madison
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06312176

Palazestrant in Combination With Ribociclib for the First-line Treatment of ER+/HER2- Advanced Breast Cancer

  • Clinical Trial Site, Milwaukee
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07085767

Signatera-Guided CDK4/6 Inhibitor Therapy in Breast Cancer

  • University of Wisconsin, Madison
Recruiting
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07214532

A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)

  • ThedaCare Physicians - Appleton North, Appleton
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07174336

A Study of LY4337713 in Participants With FAP-Positive Solid Tumors

  • University of Wisconsin - Carbone Cancer Center, Madison
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07213791

ROSETTA Breast-01: The Effects and Safety of Pumitamig in Patients With Triple-Negative Breast Cancer

  • Medical College of Wisconsin, Milwaukee
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07173751

A Phase 1/2 Trial of TER-2013 in Patients With Solid Tumors Harboring AKT/PI3K/PTEN Pathway Alterations

  • Froedtert & MCW Cancer Center, Milwaukee
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07109726

A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence

  • Mayo Clinic Health System - Eau Claire, Eau Claire
  • Mayo Clinic Health System - La Crosse, La Crosse
  • University of Wisconsin Carbone Cancer Center- University Hospital, Madison
  • and 1 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT06492616

Study of AMXT 1501 and DFMO in Combination With Standard Therapies in Advanced Solid Tumors

  • University of Wisconsin-Madison Carbone Cancer Center, Madison
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT07287917

Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer

  • University of Wisconsin Carbone Cancer Center- University Hospital, Madison
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT06982521

Evaluating Minimal Residual Disease (MRD) Through Longitudinal Circulating Tumor DNA (ctDNA) Profiling in Breast Malignancies

  • Gunderson Health, La Crosse
RecruitingObservational study
Ages 18 to 99 · All sexes · Updated Sep 3, 2026 · NCT07211178

Trial of Pre-operative Neratinib and Endocrine Therapy With Trastuzumab in ER-Positive, HER-2 Positive Breast Cancers

  • University of Wisconsin, Madison
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT04886531

The Vanguard Study: Testing a New Way to Screen for Cancer

  • Zablocki Veterans Administration Medical Center, Milwaukee
RecruitingHealthy volunteers welcome
Ages 45 to 75 · All sexes · Updated Sep 2, 2026 · NCT06995898

Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25

  • Aspirus Cancer Care-Antigo-Volm Cancer Center, Antigo
  • ThedaCare Regional Cancer Center, Appleton
  • Duluth Clinic Ashland, Ashland
  • and 59 more
RecruitingPhase 3
Ages 18 to 60 · Women · Updated Sep 2, 2026 · NCT05879926

Study of the Bria-IMT Regimen and CPI vs Physicians' Choice in Advanced Metastatic Breast Cancer.

  • Sheboygan Cancer & Blood Specialists, Sheboygan
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT06072612

Study of 18F-FFNP Breast PET/MRI

  • UW Carbone Cancer Center, Madison
RecruitingPhase 2
Ages 18 and older · Women · Updated Aug 31, 2026 · NCT06086704

Safety, PK and Efficacy of QXL138AM in Patients With Solid Tumors and Multiple Myeloma

  • Froedtert Hospital & the Medical College of Wisconsin, Milwaukee
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 27, 2026 · NCT06582017

Biomarkers to Detect Endocrine Therapy Resistance

  • UW Carbone Cancer Center, Madison
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Aug 25, 2026 · NCT06067503

Dosing Physical Activity Among Older Cancer Survivors Who Experience Chronic Pain: a Micro-randomized Trial

  • Froedtert Hospital, Milwaukee
Recruiting
Ages 65 and older · All sexes · Updated Aug 20, 2026 · NCT07227077

Impact of Intermittent Fasting on Biomarkers of Inflammation and Health-Related Quality of Life: A Feasibility Trial for Women With HR+/HER2- Early Breast Cancer

  • Froedtert Hospital & the Medical College of Wisconsin, Milwaukee
Recruiting
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT06106477

E-Mindfulness Approaches for Living After Breast Cancer

  • Aspirus Cancer Care-Antigo-Volm Cancer Center, Antigo
  • ThedaCare Regional Cancer Center, Appleton
  • ThedaCare Cancer Care - Berlin, Berlin
  • and 21 more
RecruitingPhase 3
Ages 18 to 50 · All sexes · Updated Aug 4, 2026 · NCT06748222

Integrated Cancer Repository for Cancer Research

  • Bellin Memorial Hospital, Green Bay
RecruitingObservational studyHealthy volunteers welcome
Ages 19 to 110 · All sexes · Updated Jun 29, 2026 · NCT02012699

Real-Time MRI-Guided 3-Fraction Accelerated Partial Breast Irradiation in Early Breast Cancer

  • University of Wisconsin Carbone Cancer Center, Madison
RecruitingPhase 2
Ages 40 and older · Women · Updated Jun 11, 2026 · NCT03936478

De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)

  • Langlade Hospital and Cancer Center, Antigo
  • Aurora Cancer Care-Southern Lakes VLCC, Burlington
  • Marshfield Medical Center-EC Cancer Center, Eau Claire
  • and 43 more
RecruitingPhase 3
Ages 50 to 70 · All sexes · Updated Apr 23, 2026 · NCT04852887

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

  • Aspirus Langlade Hospital, Antigo
  • ThedaCare Regional Cancer Center, Appleton
  • Ascension Saint Elizabeth Hospital, Appleton
  • and 61 more
RecruitingObservational study
Ages 18 and older · All sexes · Updated Mar 17, 2026 · NCT06418204

The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac Study

  • Medical College of Wisconsin, Milwaukee
RecruitingObservational study
Ages 18 and older · All sexes · Updated Mar 5, 2026 · NCT04075305

Safety Study of MELK Inhibitor to Treat Patients With Advanced Breast Cancer and Triple Negative Breast Cancer

  • Froedtert Hospital & the Medical College of Wisconsin, Milwaukee
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Feb 25, 2026 · NCT02926690

Effect on Body Movement and Mental Skills in Patients Who Received Gadolinium-based Contrast Media for Magnetic Resonance Examination Multiple Times Within 5 Years

  • University of Wisconsin, Madison
RecruitingPhase 4
Ages 18 to 64 · All sexes · Updated Jan 22, 2026 · NCT04373564

EXActDNA-003 / NSABP B-64: Study of Molecular Residual Disease Detection in Breast Cancer (MRD)

  • Aurora Cancer Care - Wauwatosa, Wauwatosa
RecruitingObservational study
Ages 18 and older · All sexes · Updated Jan 20, 2026 · NCT06401421

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

  • Massive Bio SYNERGY-AI site, Milwaukee
RecruitingObservational study
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

Molecular Analyses to Predict Pathways of Endocrine Resistance Following Short Term Neoadjuvant Endocrine Treatment in Patients With Hormone Receptor-Positive HER2-negative Breast Cancer

  • Froedtert Hospital and the Medical College of Wisconsin, Milwaukee
RecruitingPhase 2
Ages 18 and older · Women · Updated Oct 14, 2025 · NCT06361940

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.