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Cancer (all types) clinical trials in Minnesota

50 studies for Cancer (all types) are looking for participants at sites in Minnesota.

Cities in Minnesota

A Phase 3 Study of Ersodetug in Patients With Tumor Hyperinsulinism

  • Investigative Site, Rochester
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT06881992

Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing

  • Mayo Clinic Rochester, Rochester
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT04981119

A Study of JNJ-1761981 in Participants With Solid Tumors

  • Mayo Clinic Rochester, Rochester
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07525141

A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue

  • Mayo Clinic Cancer Center Outpatient Pharmacy, Rochester
  • Mayo Clinic, Rochester
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06989437

A Study of Zolbetuximab Together With Pembrolizumab and Chemotherapy in Adults With Gastric Cancer

  • Metro Minnesota Community Oncology Research Consortium (MMCORC), Saint Louis Park
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT06901531

A Study to Evaluate Adverse Events and Change in Disease Activity of Intravenous ABBV-706 Versus Standard of Care in Adult Participants With Relapsed/Refractory Small Cell Lung Cancer

  • Minnesota Oncology - Edina Clinic /ID# 280698, Edina
  • Mayo Clinic Hospital Rochester /ID# 279784, Rochester
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07365241

Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells

  • M Health Fairview University of Minnesota Medical Center - East Bank, Minneapolis
  • Mayo Clinic, Rochester
RecruitingPhase 2/3
All ages · All sexes · Updated Sep 18, 2026 · NCT03435796

Connect for Cancer Prevention Study (Connect)

  • HealthPartners, Minneapolis
RecruitingObservational studyHealthy volunteers welcome
Ages 30 to 70 · All sexes · Updated Sep 17, 2026 · NCT04609072

Statins to Prevent Cancer Associated Blood Clots

  • Mayo Clinic, Rochester
RecruitingPhase 4
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT07303816

Biomarkers of Resiliency In Childhood Cancer Surgery

  • Mayo Clinic, Rochester
RecruitingObservational study
Ages 3 to 25 · All sexes · Updated Sep 14, 2026 · NCT06674811

A Study to Investigate Safety and Effectiveness of Tacabrutideg (BGB-16673) in Combination With Other Agents in Participants With Relapsed or Refractory B-Cell Malignancies

  • Mayo Clinic Rochester, Rochester
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 11, 2026 · NCT06634589

A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

  • Allina Health Cancer Institute - Abbott Northwestern Hospital, Minneapolis
  • HealthPartners Cancer Research Center, Saint Paul
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06119581

A Longitudinal Multi-Omic Biomarker Profiling Study of Patients With Head & Neck Squamous Cell Carcinoma (HNSCC)

  • Mayo Clinic Rochester, Rochester
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT06163534

Study of the Bria-IMT Regimen and CPI vs Physicians' Choice in Advanced Metastatic Breast Cancer.

  • Mayo Clinic-Comprehensive Cancer Center-Breast Clinic, Rochester
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT06072612

Project: Every Child for Younger Patients With Cancer

  • Children's Hospitals and Clinics of Minnesota - Minneapolis, Minneapolis
  • University of Minnesota/Masonic Cancer Center, Minneapolis
  • Mayo Clinic in Rochester, Rochester
RecruitingObservational study
Up to age 25 · All sexes · Updated Aug 25, 2026 · NCT02402244

Abatacept in Immune Checkpoint Inhibitor Myocarditis

  • Mayo Clinic, Rochester
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 20, 2026 · NCT05335928

FOG-001 in Locally Advanced or Metastatic Solid Tumors

  • M Health Fairview University of Minnesota Medical Center, Minneapolis
  • Mayo Clinic, Rochester
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT05919264

A Master Protocol (LY900023) That Includes Several Clinical Trials of Drugs for Children and Young Adults With Cancer

  • University of Minnesota Hospital, Minneapolis
RecruitingPhase 2
Ages 1 to 39 · All sexes · Updated Aug 7, 2026 · NCT05999994

Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer

  • Riverwood Healthcare Center, Aitkin
  • Essentia Health - Baxter Clinic, Baxter
  • Sanford Joe Lueken Cancer Center, Bemidji
  • and 48 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 7, 2026 · NCT06580314

A Study of ASP1002 in Adults for Treatment of Solid Tumors

  • HealthPartners Cancer Research Center, Saint Paul
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jul 23, 2026 · NCT05719558

Relacorilant in Combination With Different Treatment Regimens in Patients With Gynecological Cancers

  • 518, Minneapolis
RecruitingPhase 2
Ages 18 and older · Women · Updated Jul 16, 2026 · NCT06906341

Capturing Food Intake in Patients Undergoing Radiation Therapy for Cancer

  • University Of Minnesota, Minneapolis
Recruiting
Ages 18 and older · All sexes · Updated Jul 14, 2026 · NCT07682714

A Study to Assess Adverse Events of Intravenously (IV) Infused Etentamig (ABBV-383) in Adult Participants With Relapsed or Refractory Multiple Myeloma

  • Mayo Clinic - Rochester /ID# 251164, Rochester
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jul 13, 2026 · NCT05650632

Collection of Blood From Healthy Patients, Patients With Benign Disease and Patients With Cancer

  • Allina Health, Virginia Piper Cancer Institute, Coon Rapids
  • Virginia Piper Cancer Institute Mercy Hospital-Unity Campus, Fridley
  • VPCI Oncology Research, Minneapolis
RecruitingObservational study
Ages 18 and older · All sexes · Updated Jul 10, 2026 · NCT05181826

A Clinical Study of KTX-2001 in Subjects With Metastatic Castration-Resistant Prostate Cancer (STRIKE-001)

  • Mayo Clinic, Rochester
RecruitingPhase 1
Ages 18 and older · Men · Updated Jul 9, 2026 · NCT07103018

A Study to Evaluate the Safety,Tolerability, Pharmacokinetics and Clinical Activity of Mocertatug Rezetecan for Injection in Participants With Advanced Solid Tumors (BEHOLD-1)

  • GSK Investigational Site, Minneapolis
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 25, 2026 · NCT06431594

Childhood Cancer Survivor Study

  • Children's Hospitals & Clinics of Minnesota, Minneapolis
RecruitingObservational studyHealthy volunteers welcome
All ages · All sexes · Updated Jun 17, 2026 · NCT01120353

A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression

  • Mayo Clinic Rochester, Rochester
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Jun 12, 2026 · NCT06051695

Patient Derived Preclinical Models

  • Mayo Clinic in Rochester, Rochester
RecruitingObservational study
Ages 18 and older · All sexes · Updated Jun 9, 2026 · NCT05324553

Study of Onivyde With Talazoparib or Temozolomide in Children With Recurrent Solid Tumors and Ewing Sarcoma

  • Children's Hospital and Clinics of Minn, Minneapolis
RecruitingPhase 1/2
12 Months – 30 Years · All sexes · Updated May 19, 2026 · NCT04901702

The Sarah Nanotechnology System for Treatment of Advanced Metastatic Solid Tumors Using Hyperthermia.

  • Mayo Clinic, Rochester
Recruiting
Ages 18 and older · All sexes · Updated May 15, 2026 · NCT07224464

A First-in-Human (FIH) Study to Evaluate the Safety and Tolerability of VVD-130037 in Participants With Advanced Solid Tumors

  • Mayo Clinic Rochester, Rochester
RecruitingPhase 1
Ages 18 and older · All sexes · Updated May 8, 2026 · NCT05954312

I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer

  • University of Minnesota, Minneapolis
  • Mayo Clinic, Rochester
  • Metro Minnesota Community Oncology Research Consortium, Hennepin County Medical Center, Saint Louis Park
RecruitingPhase 2
Ages 18 and older · All sexes · Updated May 6, 2026 · NCT01042379

Axelopran for Advanced Cancer in Patients Receiving Opioids

  • HealthPartners Frauenshuh Cancer Research Center, Saint Louis Park
  • HealthPartners Cancer Center at Regions Hospital, Saint Paul
RecruitingPhase 2
Ages 18 and older · All sexes · Updated May 5, 2026 · NCT07354919

CA-4948-101: Open-Label, Dose Escalation and Expansion Trial of Emavusertib (CA-4948) in Relapsed or Refractory Primary Central Nervous System Lymphoma (R/R PCNSL)

  • Mayo Clinic, Rochester
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Apr 16, 2026 · NCT03328078

INTERogating Cancer for Etiology, Prevention and Therapy Navigation

  • Mayo Clinic in Rochester, Rochester
RecruitingObservational study
Ages 18 and older · All sexes · Updated Apr 7, 2026 · NCT06008392

Multi-Cancer Detection Observational Cohort Study

  • Mayo Clinic in Rochester, Rochester
RecruitingObservational studyHealthy volunteers welcome
Ages 21 and older · All sexes · Updated Apr 6, 2026 · NCT06962995

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.