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Lung Cancer clinical trials in Dayton, OH

14 studies for Lung Cancer are looking for participants at sites in and around Dayton (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

RecruitingPhase 3
  • Miami Valley Hospital, Dayton
  • Dayton Physician LLC - Englewood, Dayton
  • Miami Valley Hospital North, Dayton
  • and 4 more
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT04267848

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Dayton Physician LLC - Englewood, Dayton
  • Greater Dayton Cancer Center, Kettering · 5 mi away
  • Kettering Medical Center, Kettering · 5 mi away
  • and 4 more
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

Chemotherapy Combined With Immunotherapy Versus Immunotherapy Alone for Older Adults With Stage IIIB-IV Lung Cancer, The ACHIEVE Trial

RecruitingPhase 3
  • Miami Valley Hospital, Dayton
  • Premier Blood and Cancer Center, Dayton
  • Miami Valley Hospital North, Dayton
  • and 3 more
Ages 70 and older · All sexes · Updated Oct 1, 2026 · NCT06096844

Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancer

RecruitingPhase 3
  • Miami Valley Hospital, Dayton
  • Premier Blood and Cancer Center, Dayton
  • Miami Valley Hospital North, Dayton
  • and 4 more
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT04181060

Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial

RecruitingPhase 3
  • Miami Valley Hospital, Dayton
  • Miami Valley Hospital North, Dayton
  • Miami Valley Hospital South, Centerville · 9 mi away
  • and 1 more
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06498635

Safety, Efficacy, and Pharmacokinetics of BNT327 in Combination With Chemotherapy and Other Investigational Agents for Lung Cancer

RecruitingPhase 2/3
  • Dayton Physicians Network, Dayton
  • Kettering Medical Center, Kettering · 5 mi away
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06712316

A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

RecruitingPhase 3
  • Miami Valley Hospital South, Centerville · 9 mi away
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06119581

Safety and Efficacy of BNT327, an Investigational Therapy in Combination With Chemotherapy for Patients With Untreated Small-cell Lung Cancer

RecruitingPhase 3
  • Kettering Medical Center, Kettering · 5 mi away
Ages 18 and older · All sexes · Updated Sep 1, 2026 · NCT06712355

Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer

RecruitingPhase 3
  • Miami Valley Hospital, Dayton
  • Premier Blood and Cancer Center, Dayton
  • Miami Valley Hospital North, Dayton
  • and 3 more
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT05624996

Comparing Combinations of Targeted Drugs for Advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes (A Lung-MAP Treatment Trial)

RecruitingPhase 2
  • Miami Valley Hospital, Dayton
  • Premier Blood and Cancer Center, Dayton
  • Miami Valley Hospital North, Dayton
  • and 4 more
Ages 18 and older · All sexes · Updated Jun 3, 2026 · NCT05642572

Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has a MET Exon 14 Skipping Gene Change (An Expanded Lung-MAP Treatment Trial)

RecruitingPhase 2
  • Miami Valley Hospital, Dayton
  • Premier Blood and Cancer Center, Dayton
  • Miami Valley Hospital North, Dayton
  • and 3 more
18 Minutes · All sexes · Updated May 5, 2026 · NCT06031688

Adding the Immunotherapy Drug Cemiplimab to Usual Treatment for People With Advanced Non-Small Cell Lung Cancer Who Had Previous Treatment With Platinum Chemotherapy and Immunotherapy (An Expanded Lung-MAP Treatment Trial)

RecruitingPhase 2/3
  • Miami Valley Hospital, Dayton
  • Premier Blood and Cancer Center, Dayton
  • Miami Valley Hospital North, Dayton
  • and 3 more
Ages 18 and older · All sexes · Updated May 5, 2026 · NCT06616584

About Lung Cancer

Lung cancer forms in tissues of the lung, usually in the cells that line the air passages. It is the leading cause of cancer death in both men and women.

More about Lung Cancer on MedlinePlus

Lung Cancer trials in other cities

Other studies in Dayton

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.