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A Study of the Drug Selinexor With Radiation Therapy in Patients With Newly-Diagnosed Diffuse Intrinsic Pontine (DIPG) Glioma and High-Grade Glioma (HGG)

  • Geisinger Medical Center, Danville
  • Children's Hospital of Philadelphia, Philadelphia
  • Saint Christopher's Hospital for Children, Philadelphia
  • ak 1 plis
Ap rekriteFaz 1/2
12 Months – 21 Years · Tout sèks · Mizajou Oct 1, 2026 · NCT05099003

Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII

  • Thomas Jefferson University, Sidney Kimmel Comprehensive Cancer Center, Philadelphia
  • UPMC Hillman Cancer Center, Pittsburgh
Ap rekriteFaz 2
Laj 18 ak plis · Tout sèks · Mizajou Sep 28, 2026 · NCT07326566

A Study of Repotrectinib in Pediatric and Young Adult Subjects Harboring ALK, ROS1, OR NTRK1-3 Alterations

  • Children's Hospital of Philadelphia-Center for Childhood Cancer Research, Philadelphia
Ap rekriteFaz 1/2
Jiska laj 25 · Tout sèks · Mizajou Sep 25, 2026 · NCT04094610

Evaluation of 18F-Fluciclovine Positron Emission Tomography - Magnetic Resonance Imaging (PET-MRI) in LGG

  • The Children s Hospital of Philadelphia, Philadelphia
Ap rekriteFaz 1 bonè
Laj 1 a 21 · Tout sèks · Mizajou Sep 22, 2026 · NCT05555550

ACT001 for the Treatment of Diffuse Intrinsic Pontine Gliomas and H3K27-altered High Grade Gliomas

  • Children's Hospital of Philidelphia, Philidelphia
Ap rekriteFaz 2
12 Months – 39 Years · Tout sèks · Mizajou Sep 21, 2026 · NCT06838676

Targeted Pediatric High-Grade Glioma Therapy

  • Children's Hospital of Philadelphia, Philadelphia
Ap rekriteEtid obsèvasyon
12 Months – 39 Years · Tout sèks · Mizajou Sep 8, 2026 · NCT05839379

Study of Olutasidenib and Temozolomide in HGG

  • Children's Hospital of Philadelphia, Philadelphia
Ap rekriteFaz 2
Laj 12 a 39 · Tout sèks · Mizajou Sep 1, 2026 · NCT06161974

SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance)

  • Thomas Jefferson University Hospital, Philadelphia
  • UPMC Hillman Cancer Center, Pittsburgh
Ap rekriteFaz 3
Laj 18 ak plis · Tout sèks · Mizajou Aug 28, 2026 · NCT05303519

PEP-CMV Vaccine Targeting CMV Antigen to Treat Newly Diagnosed Pediatric HGG and DIPG and Recurrent Medulloblastoma

  • Children's Hospital of Philadelphia, Philadelphia
Ap rekriteFaz 2
Laj 3 a 39 · Tout sèks · Mizajou Aug 24, 2026 · NCT05096481

Trametinib and Everolimus for Treatment of Pediatric and Young Adult Patients With Recurrent Gliomas (PNOC021)

  • Children's Hospital of Philadelphia, Philadelphia
Ap rekriteFaz 1
Laj 1 a 25 · Tout sèks · Mizajou Aug 18, 2026 · NCT04485559

A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations

  • Thomas Jefferson University, Philadelphia
Ap rekriteFaz 2
Laj 8 ak plis · Tout sèks · Mizajou Jul 27, 2026 · NCT05503797

Pembrolizumab, Olaparib, and Temozolomide for People With Glioma

  • Lehigh Valley Health Network (Data Collection Only), Allentown
Ap rekriteFaz 2
Laj 18 ak plis · Tout sèks · Mizajou Jul 22, 2026 · NCT05188508

Lutathera for Treatment of Recurrent or Progressive High-Grade CNS Tumors

  • Children's Hospital of Philadelphia, Philadelphia
Ap rekriteFaz 1/2
Laj 4 a 39 · Tout sèks · Mizajou Jul 20, 2026 · NCT05278208

Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion

  • Children's Hospital of Philadelphia, Philadelphia
Ap rekriteFaz 1 bonèVolontè an sante akeyi
Laj 1 a 21 · Tout sèks · Mizajou Jun 29, 2026 · NCT06333899

Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant

  • Children's Hospital of Philadelphia, Philadelphia
Ap rekriteFaz 2
12 Months – 39 Years · Tout sèks · Mizajou May 29, 2026 · NCT05843253

A Study to Investigate the Safety and Efficacy of NST-628 Oral Tablets in Subjects With Solid Tumors

  • UPMC Hillman Cancer Center, Pittsburgh
Ap rekriteFaz 1
Laj 18 ak plis · Tout sèks · Mizajou Apr 20, 2026 · NCT06326411

A Pilot Study of Larotrectinib for Newly-Diagnosed High-Grade Glioma With NTRK Fusion

  • Children's Hospital of Philadelphia, Philadelphia
Ap rekriteFaz 1 bonè
Jiska laj 21 · Tout sèks · Mizajou Mar 18, 2026 · NCT04655404

All-Trans Retinoic Acid (ATRA) Plus PD-1 Inhibition in Recurrent IDH-Mutant Glioma

  • University of Pennsylvania, Philadelphia
Ap rekriteFaz 2
Laj 18 ak plis · Tout sèks · Mizajou Feb 20, 2026 · NCT05345002

18F-Fluciclovine PET-MRI in High-grade Glioma

  • Children's Hospital of Philadelphia, Philadelphia
Ap rekriteFaz 1 bonè
Laj 1 a 21 · Tout sèks · Mizajou Dec 4, 2025 · NCT05553041

Sous ClinicalTrials.gov, done yo ranmase Oct 5, 2026. Chak etid gen kritè li pou li menm; ekip etid la deside ki moun ki ka patisipe.