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Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

피험자 모집 중2상
  • Tufts Medical Center, Boston
  • Dana-Farber Cancer Institute, Boston
전 연령 · 모든 성별 · 2026. 10. 2. 업데이트됨 · NCT05564377

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

피험자 모집 중1/2상
  • Massachusetts General Hospital, Boston
  • Dana Farber Cancer Institute, Boston
12세 이상 · 모든 성별 · 2026. 10. 2. 업데이트됨 · NCT04585750

Distance-Based Exercise to Preserve Function and Prevent Disability

피험자 모집 중
  • Dana-Farber Cancer Institute, Boston
18세 이상 · 모든 성별 · 2026. 10. 2. 업데이트됨 · NCT07059884

Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Carboplatin and Paclitaxel) Combined With Immunotherapy (Pembrolizumab) for pMMR, TP53 Mutated Endometrial Cancer

피험자 모집 중3상
  • Dana-Farber Cancer Institute, Boston
18세 이상 · 여성 · 2026. 10. 2. 업데이트됨 · NCT07198074

A Study to Learn More About How Well Treatment With Sevabertinib (BAY 2927088) Tablets Works and How Safe it is in Participants Who Have a Solid Tumor With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)

피험자 모집 중2상
  • Dana-Farber Cancer Institute - Oncology Department, Boston
18세 이상 · 모든 성별 · 2026. 10. 2. 업데이트됨 · NCT06760819

A Study With NKT3964 for Adults With Advanced/Metastatic Solid Tumors

피험자 모집 중1상
  • Dana Farber Cancer Institute, Boston
19세 이상 · 모든 성별 · 2026. 10. 1. 업데이트됨 · NCT06586957

Phase 1 Study to Investigate TCRTs KRAS Mutation in Unresectable, Advanced, and/or Metastatic Solid Tumors

피험자 모집 중1상
  • Research Site, Boston
18세 이상 · 모든 성별 · 2026. 9. 25. 업데이트됨 · NCT06218914

Study of REGN4018 (Ubamatamab) Administered Alone or in Combination With Cemiplimab in Adult Patients With Recurrent Ovarian Cancer or Other Recurrent Mucin-16 Expressing (MUC16+) Cancers

피험자 모집 중1/2상
  • Massachusetts General Hospital, Boston
  • Dana Farber / Harvard Cancer Center, Boston
18세 이상 · 여성 · 2026. 9. 25. 업데이트됨 · NCT03564340

A Study to Find Out How Safe REGN5668 is and How Well it Works In Adult Women When Given With Either Cemiplimab, or Cemiplimab + Fianlimab, or Ubamatamab

피험자 모집 중1/2상
  • Massachusetts General Hospital, Boston
  • Dana Farber Cancer Institute Brookline Avenue, Boston
18세 이상 · 여성 · 2026. 9. 24. 업데이트됨 · NCT04590326

Adjuvant Therapy in POLE-Mutated and p53-Wildtype/NSMP Early Stage Endometrial Cancer RAINBO BLUE & TAPER

피험자 모집 중2상
  • Massachusetts General Hospital Cancer Center, Boston
18세 이상 · 여성 · 2026. 9. 24. 업데이트됨 · NCT05640999

Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

피험자 모집 중1/2상
  • Dana Farber Cancer Institute, Boston
18세 이상 · 모든 성별 · 2026. 9. 22. 업데이트됨 · NCT06128551

A Study of LY4257496 in Participants With Cancer (OMNIRAY)

피험자 모집 중1상
  • Massachusetts General Hospital, Boston
  • Dana-Farber Cancer Institute, Boston
18세 이상 · 모든 성별 · 2026. 9. 22. 업데이트됨 · NCT07114601

Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors

피험자 모집 중1상
  • Massachusetts General Hospital, Boston
  • Dana-Farber Cancer Institute, Boston
18세 이상 · 모든 성별 · 2026. 9. 21. 업데이트됨 · NCT05983432

A Phase 1/2 Trial of TER-2013 in Patients With Solid Tumors Harboring AKT/PI3K/PTEN Pathway Alterations

피험자 모집 중1/2상
  • Massachusetts General Hospital, Boston
18세 이상 · 모든 성별 · 2026. 9. 17. 업데이트됨 · NCT07109726

ALPINE: Maintenance Letrozole/Abemaciclib

피험자 모집 중2상
  • Beth Israel Deaconess Medical Center, Boston
  • Brigham and Women's Hospital, Boston
  • Dana-Farber Cancer Institute, Boston
18세 이상 · 모든 성별 · 2026. 9. 16. 업데이트됨 · NCT06366347

A Phase I/IIa Study of AZD8205 Given Alone or Combined, in Participants With Advanced/Metastatic Solid Malignancies

피험자 모집 중1/2상
  • Research Site, Boston
18세 이상 · 모든 성별 · 2026. 9. 11. 업데이트됨 · NCT05123482

Open Label Study to Evaluate BL-M07D1 in HER2 Expressing Malignant Solid Tumors

피험자 모집 중1상
  • Dana Farber Cancer Institute, Boston
18세 이상 · 모든 성별 · 2026. 9. 10. 업데이트됨 · NCT06293898

Phase 1 Study to Assess Safety, Tolerability, Pharmacokinetics, Immunogenicity, and Antitumor Activity of ARR-002 in Advanced or Metastatic Ovarian or Endometrial Cancer.

피험자 모집 중1상
  • Dana-Farber Cancer Institute, Boston
18세 이상 · 여성 · 2026. 9. 3. 업데이트됨 · NCT07755436

A Phase 1 Study of CTIM-76 in Patients With Recurring Ovarian Cancer and Other Advanced Solid Tumors

피험자 모집 중1상
  • Dana-Farber Cancer Institute, Boston
18세 이상 · 모든 성별 · 2026. 9. 3. 업데이트됨 · NCT06515613

Concurrent Laparoscopic Hysterectomy and Weight Loss Surgery in Obese Patients With Endometrial Carcinoma or Endometrial Intraepithelial Neoplasia

피험자 모집 중
  • Brigham and Women's Hospital, Boston
  • Dana-Farber Cancer Institute, Boston
18세 이상 · 여성 · 2026. 8. 31. 업데이트됨 · NCT04839614

A Study of STRO-004 in Adults With Refractory/Recurrent Metastatic Cancer

피험자 모집 중1상
  • Mass General Cancer Center, Boston
18세 이상 · 모든 성별 · 2026. 8. 27. 업데이트됨 · NCT07227168

A Study of Mutant Selective-Inhibitor (CGT6297), in Patients With Advanced Solid Tumors

피험자 모집 중1상
  • Dana-Farber Cancer Institute, Boston
18세 이상 · 모든 성별 · 2026. 8. 26. 업데이트됨 · NCT07383506

Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

피험자 모집 중1/2상
  • Dana-Farber Cancer Institute, Boston
12 Months – 30 Years · 모든 성별 · 2026. 8. 25. 업데이트됨 · NCT04851119

A Phase 1 Study of LNCB74 in Advanced Solid Tumors

피험자 모집 중1상
  • Dana Farber Cancer Institute, Boston
18세 이상 · 모든 성별 · 2026. 8. 21. 업데이트됨 · NCT06774963

Phase I/IIa Study of AZD5335 as Monotherapy and Combination Therapy in Participants With Solid Tumors

피험자 모집 중1/2상
  • Research Site, Boston
18세 ~ 130세 · 모든 성별 · 2026. 8. 21. 업데이트됨 · NCT05797168

A Phase 2 Study of ACR-368 in Endometrial Adenocarcinoma

피험자 모집 중2상
  • Dana Farber Cancer Institute, Boston
18세 이상 · 여성 · 2026. 8. 21. 업데이트됨 · NCT05548296

A Study of Tulmimetostat DZR123 (CPI-0209) in Patients With Advanced Solid Tumors and Lymphomas

피험자 모집 중1/2상
  • Massachusetts General Hospital, Boston
18세 이상 · 모든 성별 · 2026. 8. 19. 업데이트됨 · NCT04104776

A Phase 1 Study of NRM-823 in Participants With Locally Advanced or Metastatic Refractory Solid Tumors

피험자 모집 중1상
  • Normunity Investigational Site, Boston
  • Normunity Investigational Site, Boston
18세 이상 · 모든 성별 · 2026. 8. 18. 업데이트됨 · NCT07182149

FOG-001 in Locally Advanced or Metastatic Solid Tumors

피험자 모집 중1/2상
  • Massachusetts General Hospital, Boston
  • Dana Farber Cancer Institute, Boston
18세 이상 · 모든 성별 · 2026. 8. 17. 업데이트됨 · NCT05919264

A Study of PHST001 in Advanced Solid Tumors

피험자 모집 중1상
  • Dana Farber Cancer Institute, Boston
18세 이상 · 모든 성별 · 2026. 8. 12. 업데이트됨 · NCT06840886

A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors

피험자 모집 중1/2상
  • Massachusetts General Hospital Cancer Center, Boston
18세 이상 · 모든 성별 · 2026. 8. 11. 업데이트됨 · NCT05592626

Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)

피험자 모집 중1/2상
  • Massachusetts General Hospital, Boston
  • Dana Farber Cancer Institute, Boston
18세 이상 · 모든 성별 · 2026. 8. 4. 업데이트됨 · NCT05579366

First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors

피험자 모집 중1/2상
  • Massachusetts General Hospital, Boston
  • Dana-Farber Cancer Institute, Boston
18세 이상 · 모든 성별 · 2026. 7. 7. 업데이트됨 · NCT05768139

A Phase 1 Dose-escalation Trial of KST-6051 in Participants With Advanced Solid Tumors With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Mutation

피험자 모집 중1상
  • Mass General Brigham Cancer Institute at Massachusetts General Hospital, Boston
18세 이상 · 모든 성별 · 2026. 6. 29. 업데이트됨 · NCT07458347

A Study of Emiltatug Ledadotin (Emi-Le) in Participants With Solid Tumors

피험자 모집 중1/2상
  • Beth Israel Deaconess Medical Center, Boston
  • Dana-Farber Cancer Institute, Boston
18세 이상 · 모든 성별 · 2026. 6. 29. 업데이트됨 · NCT05377996

Phase 1/2 Study of ETX-636 in Participants With Advanced Solid Tumors

피험자 모집 중1/2상
  • Beth Israel Deaconess Medical Center, Boston
  • Dana-Farber Cancer Institute, Boston
18세 이상 · 모든 성별 · 2026. 6. 23. 업데이트됨 · NCT06993844

A Study of LY4175408 in Participants With Advanced Cancer

피험자 모집 중1상
  • Massachusetts General Hospital, Boston
18세 이상 · 모든 성별 · 2026. 6. 23. 업데이트됨 · NCT07046923

RESOLVE: Abemaciclib + Letrozole +/- Metformin or Gedatolisib in Endometrial Cancer

피험자 모집 중2상
  • Massachusetts General Hospital Cancer Center, Boston
  • Beth Israel Deaconess Medical Center (BIDMC), Boston
  • Dana Farber Cancer Institute, Boston
18세 이상 · 여성 · 2026. 6. 22. 업데이트됨 · NCT03675893

Menstrual Cup for Early Endometrial Cancer Detection in Lynch Syndrome

피험자 모집 중건강한 지원자 환영
  • Dana-Farber Cancer Institute, Boston
18세 이상 · 여성 · 2026. 6. 10. 업데이트됨 · NCT07220239

A Phase 1/1B Study of ST-01156, a Small Molecule RBM39 Degrader, in Patients With Advanced Solid Malignancies

피험자 모집 중1상
  • Mass General Brigham Cancer Institute, Boston
  • Dana Farber Cancer Institute, Boston
16세 이상 · 모든 성별 · 2026. 6. 2. 업데이트됨 · NCT07197554

Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors

피험자 모집 중1/2상
  • Massachusetts General Hospital, Boston
18세 이상 · 모든 성별 · 2026. 5. 6. 업데이트됨 · NCT06239194

A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies

피험자 모집 중1/2상
  • Massachusetts General Hospital, Boston
18세 이상 · 모든 성별 · 2026. 3. 27. 업데이트됨 · NCT06395519

Exercise as a Preventive Agent to Combat Immobility in Patients With Ovarian or Endometrial Cancers Receiving Chemotherapy

피험자 모집 중
  • Dana Farber Cancer Institute, Boston
18세 이상 · 여성 · 2026. 2. 19. 업데이트됨 · NCT04997096

Avelumab and M1774 in ARID1A-mutated Endometrial Cancer

피험자 모집 중2상
  • Dana-Farber Cancer Institute, Boston
  • Brigham and Women's Hospital, Boston
18세 이상 · 여성 · 2026. 1. 7. 업데이트됨 · NCT06518564

Belzutifan in Recurrent Clear Cell Carcinoma of Gynecologic Origin

피험자 모집 중2상
  • Brigham and Women's Hospital, Boston
  • Dana-Farber Cancer Institute, Boston
18세 이상 · 여성 · 2025. 11. 5. 업데이트됨 · NCT06677190

A Study to Evaluate TROP2 ADC LCB84 Single Agent and in Combination With an Anti-PD-1 Ab in Advanced Solid Tumors

피험자 모집 중1/2상
  • Dana Farber Cancer Institute, Boston
18세 이상 · 모든 성별 · 2025. 9. 24. 업데이트됨 · NCT05941507

A Study of GV20-0251 Monotherapy and GV20-0251 in Combination With Pembrolizumab in Participants With Solid Tumor Malignancies

피험자 모집 중1/2상
  • Massachusetts General Hospital, Boston
18세 이상 · 모든 성별 · 2025. 2. 13. 업데이트됨 · NCT05669430

Comprehensive Outcomes for After Cancer Health

피험자 모집 중건강한 지원자 환영
  • Dana Farber Cancer Institute, Boston
18세 이상 · 모든 성별 · 2024. 12. 11. 업데이트됨 · NCT05349227

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