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Chronic Lymphocytic Leukemia clinical trials in Charlotte, NC

9 studies for Chronic Lymphocytic Leukemia are looking for participants at sites in and around Charlotte (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

A Study to Evaluate Safety, PK, PD and Efficacy of AZD5492, a T Cell-engaging Antibody Targeting CD20 in Subjects With R/R B-Cell Malignancies.

RecruitingPhase 1/2
  • Research Site, Charlotte
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT06542250

A Study to Investigate Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax Plus Acalabrutinib in Adults With Previously Untreated Chronic Lymphocytic Leukemia

RecruitingPhase 3
  • Atrium Health Levine Cancer Institute (Lci), Charlotte
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07277231

A Study to Evaluate the Safety and Efficacy of Tacabrutideg (BGB-16673) Compared to Pirtobrutinib in Adults With Relapsed/Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

RecruitingPhase 3
  • Atrium Health Levine Cancer Institute (Lci), Charlotte
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT06973187

A Study of AZD0486 Monotherapy or in Combination With Other Anti-Cancer Agents for Mature B-Cell Malignancies

RecruitingPhase 1/2
  • Research Site, Charlotte
  • Research Site, Charlotte
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06564038

Phase 2 Study of Disease Risk Mutation-Guided Finite Acalabrutinib+Venetoclax for Relapsed CLL Post-1L Finite cBTKi+BCL2i ± Obinutuzumab

RecruitingPhase 2
  • Research Site, Charlotte
Ages 18 to 130 · All sexes · Updated Aug 6, 2026 · NCT07024706

Study to Assess Change in Disease Activity and Adverse Events of Oral Venetoclax With Intravenous (IV) Obinutuzumab in Adult Participants With Recurring Chronic Lymphocytic Leukemia (CLL)

RecruitingPhase 2
  • Novant Health Presbyterian Medical Center /ID# 230201, Charlotte
Ages 18 and older · All sexes · Updated Feb 9, 2026 · NCT04895436

Chronic Lymphocytic Leukemia trials in other cities

Other studies in Charlotte

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.