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Bile Duct Cancer (Cholangiocarcinoma) clinical trials recruiting in the U.S.

56 studies for Bile Duct Cancer (Cholangiocarcinoma) are recruiting participants at sites across the United States.

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Recently updated studies

Obtaining Solid Tumor Tissue From People Having Biopsy or Surgery for Certain Types of Cancer

RecruitingObservational study
Ages 2 and older · All sexes · Updated Oct 5, 2026 · NCT01915225

A Study of PHST001 in Advanced Solid Tumors

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT06840886

A Phase 1 Study of PLN-101095 in Adults With Advanced or Metastatic Solid Tumors

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06270706

Evaluating Efficacy of Tivozanib (AV-951) in Biliary Tract Cancers

RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT04645160

Pemigatinib + Afatinib in Advanced Refractory Solid Tumors

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT06302621

Trifluridine/Tipiracil + Oxaliplatin in Participants With Advanced or Metastatic Biliary Tract Cancer

RecruitingPhase 2
Ages 19 and older · All sexes · Updated Sep 22, 2026 · NCT07146646

A Study of LY4337713 in Participants With FAP-Positive Solid Tumors

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07213791

A Study of ASP546C in Adults With Gastroesophageal Cancer, Pancreatic Cancer or Other Solid Tumors

RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07488676

Alternating Chemo-immunotherapy and FGFR Inhibitor for FGFR-positive Biliary or Cholangiocarcinoma

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT07780838

Safety and Tolerability of TNG462 in Patients With MTAP-deleted Solid Tumors

RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT05732831

Pilot Comparing ctDNA IDV vs. SPV Sample in Pts Undergoing Biopsies for Hepatobiliary and Pancreatic Cancers

Recruiting
Ages 18 and older · All sexes · Updated Aug 31, 2026 · NCT05497531

Olutasidenib DDI Study in Patients With IDH1 Mutation Positive Malignancies

RecruitingPhase 4
Ages 18 and older · All sexes · Updated Aug 11, 2026 · NCT07486713

TCR1188-ABC Cells in KRAS-mutated Cancers

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 6, 2026 · NCT07594067

D07001 Softgel-Capsules and Capecitabine Combination Therapy in Patients With Advanced Biliary Tract Cancer

RecruitingPhase 3
Ages 18 and older · All sexes · Updated Jul 30, 2026 · NCT06622057

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.