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Liver Cancer (Hepatocellular Carcinoma) clinical trials in Maryland

16 studies for Liver Cancer (Hepatocellular Carcinoma) are looking for participants at sites in Maryland.

Cities in Maryland

The Vanguard Study: Testing a New Way to Screen for Cancer

  • Walter Reed National Military Medical Center, Bethesda
RecruitingHealthy volunteers welcome
Ages 45 to 75 · All sexes · Updated Oct 5, 2026 · NCT06995898

Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors

  • Exelixis Clinical Site #14, Baltimore
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT05176483

Study of the Theranostic Pair RYZ811 (Diagnostic) and RYZ801 (Therapeutic) to Identify and Treat Subjects With GPC3+ (Glypican-3) Unresectable HCC

  • Research Facility, Baltimore
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT06726161

Safety and Preliminary Anti-Tumor Activity of TYRA-430 in Advanced Hepatocellular Carcinoma and Other Solid Tumors With Activating FGF/FGFR Pathway Aberrations

  • John Hopkins University, Baltimore
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT06915753

A Study of Therapeutic Drug Monitoring-Based Atezolizumab Dosing

  • National Institutes of Health Clinical Center, Bethesda
RecruitingPhase 1
Ages 18 to 120 · All sexes · Updated Sep 22, 2026 · NCT06066138

Real-world Evaluation of the HistoSonics Edison System for Treatment of Liver Tumors Across Multidisciplinary Users (BOOMBOX: Master Study)

  • Johns Hopkins Hospital, Baltimore
RecruitingObservational study
Ages 22 and older · All sexes · Updated Sep 11, 2026 · NCT06486454

FOG-001 in Locally Advanced or Metastatic Solid Tumors

  • Johns Hopkins University, The Sidney Kimmel Comprehensive Cancer Center, Baltimore
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT05919264

First in Human Study to Evaluate AZD9793 in Participants With Advanced or Metastatic Solid Tumours

  • Research Site, Baltimore
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 13, 2026 · NCT06795022

A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations

  • The John Hopkins Hospital, Baltimore
  • Maryland Oncology Hematology- Columbia, Rockville
RecruitingPhase 2
Ages 8 and older · All sexes · Updated Jul 27, 2026 · NCT05503797

Preventing Liver Cancer Mortality Through Imaging With Ultrasound vs. MRI

  • Baltimore VA Medical Center VA Maryland Health Care System, Baltimore, MD, Baltimore
Recruiting
Ages 18 to 75 · All sexes · Updated Jun 17, 2026 · NCT05486572

DB-1311 in Combination With BNT327 or DB-1305 in Advanced/Metastatic Solid Tumors

  • USA11-0, Bethesda
RecruitingPhase 2
Ages 18 and older · All sexes · Updated May 22, 2026 · NCT06953089

18F-Fibroblast Activation Protein Inhibitor ([18F]FAPI-74) PET Imaging for Cancer Detection

  • National Institutes of Health Clinical Center, Bethesda
RecruitingPhase 2
Ages 18 to 120 · All sexes · Updated May 19, 2026 · NCT06503146

A Study of TTI-101 as Monotherapy and in Combination in Participants With Locally Advanced or Metastatic, and Unresectable Hepatocellular Carcinoma

  • The Sidney Kimmel Comprehensive Cancer Center, Baltimore
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Apr 27, 2026 · NCT05440708

GPC3 Targeted CAR-T Cell Therapy in Advanced GPC3 Expressing Solid Tumor Malignancies

  • National Institutes of Health Clinical Center, Bethesda
RecruitingPhase 1
Ages 18 to 120 · All sexes · Updated Apr 7, 2026 · NCT05003895

Study of RP2 in Combination With Second-line Therapy in Patients With Locally Advanced or Metastatic HCC

  • University of Maryland Medical Center, Baltimore
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Apr 2, 2026 · NCT05733598

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

  • Massive Bio SYNERGY-AI site, Baltimore
  • Massive Bio SYNERGY-AI site, Bethesda
  • Massive Bio SYNERGY-AI site, Silver Spring
  • and 1 more
RecruitingObservational study
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.