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Clear-cell metastatic renal cell carcinoma clinical trials recruiting in the U.S.

17 studies for Clear-cell metastatic renal cell carcinoma are recruiting participants at sites across the United States.

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Recently updated studies

Study of Casdatifan and Cabozantinib Versus Placebo and Cabozantinib in Patients With Advanced Clear Cell Renal Cell Carcinoma

RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT07011719

Casdatifan for the Treatment of Refractory Metastatic Clear Cell Renal Cell Carcinoma

RecruitingPhase 1
Ages 18 to 100 · All sexes · Updated Sep 25, 2026 · NCT07748988

Genetic Testing to Select Therapy for the Treatment of Advanced or Metastatic Kidney Cancer, OPTIC RCC Study

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT05361720

A First-in-Human Study of BMS-986506 in Participants With Advanced Clear Cell Renal Cell Carcinoma (ccRCC)

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 11, 2026 · NCT07195682

Effects of Belzutifan on 89Zr-DFO-girentuximab PET Uptake in Patients With Renal Cell Carcinoma (RCC)

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jul 30, 2026 · NCT07179770

Trial of an Alternative Cabozantinib Dosing Schedule in Metastatic Renal Cell Carcinoma and Neuroendocrine Tumors

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jul 28, 2026 · NCT05263050

Zanzalintinib for Metastatic Clear Cell Renal Cell Carcinoma With Bone Metastases

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jul 27, 2026 · NCT07043608

Imaging of Solid Tumors Using 18F-TRX

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jul 23, 2026 · NCT06942104

Adding Biotherapy or Placebo to Standard Treatment for Advanced Kidney Cancer

RecruitingPhase 3
Ages 18 and older · All sexes · Updated Jun 11, 2026 · NCT07383441

VSV-IFNβ-NIS With Ipilimumab and Nivolumab for the Treatment of Advanced or Metastatic Clear Cell Renal Cell Carcinoma

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jun 5, 2026 · NCT07510334

Immune Checkpoint Inhibitor Response in Solid Tumors Using a Live Tumor Diagnostic Platform

RecruitingObservational study
Ages 18 and older · All sexes · Updated Mar 12, 2026 · NCT06349642

CBM588 Capsules in Combination With Nivolumab and Ipilimumab for the Treatment of Advanced Stage Kidney Cancer

RecruitingPhase 1
Ages 18 and older · All sexes · Updated May 30, 2024 · NCT06399419

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.