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Cancer (all types) clinical trials in South Dakota
13 studies for Cancer (all types) are looking for participants at sites in South Dakota.
Cities in South Dakota
A Study of Ifinatamab Deruxtecan in Pediatric Participants With Relapsed or Refractory Solid Tumors (MK-9999-01D/LIGHTBEAM-U01)
- Sanford Children's Hospital ( Site 4015), Sioux Falls
RecruitingPhase 1/2
1 Month – 17 Years · All sexes · Updated Sep 25, 2026 · NCT07630974TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer
- Sanford Cancer Center Oncology Clinic and Pharmacy, Sioux Falls
RecruitingPhase 2
Ages 12 and older · All sexes · Updated Sep 22, 2026 · NCT02693535Connect for Cancer Prevention Study (Connect)
- Sanford Health, Sioux Falls
RecruitingObservational studyHealthy volunteers welcome
Ages 30 to 70 · All sexes · Updated Sep 17, 2026 · NCT04609072A Study of Patritumab Deruxtecan in Pediatric Participants With Relapsed or Refractory Solid Tumors (MK-9999-01C/LIGHTBEAM-U01)
- Sanford Children's Hospital ( Site 3015), Sioux Falls
RecruitingPhase 1/2
1 Month – 17 Years · All sexes · Updated Sep 17, 2026 · NCT06941272A Phase IIIb Study to Evaluate Camizestrant Plus Ribociclib in ER-positive, HER2-negative Advanced Breast Cancer
- Research Site, Sioux Falls
RecruitingPhase 3
Ages 18 to 130 · All sexes · Updated Sep 8, 2026 · NCT07647328A Longitudinal Multi-Omic Biomarker Profiling Study of Patients With Head & Neck Squamous Cell Carcinoma (HNSCC)
- Sanford Sioux Falls, Sioux Falls
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT06163534KEYMAKER-U01 Substudy 01J: A Study of Pembrolizumab Plus MK-1084 in Participants With Non-Small Cell Lung Cancer (NSCLC) With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) G12C Mutations (MK-3475-01J/KEYMAKER-U01J)
- Sanford Cancer Center Oncology Clinic ( Site 0038), Sioux Falls
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT07252739Project: Every Child for Younger Patients With Cancer
- Sanford USD Medical Center - Sioux Falls, Sioux Falls
RecruitingObservational study
Up to age 25 · All sexes · Updated Aug 25, 2026 · NCT02402244Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer
- Avera Cancer Institute-Aberdeen, Aberdeen
- Avera Cancer Institute - Mitchell, Mitchell
- Avera Cancer Institute at Pierre, Pierre
- and 4 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 7, 2026 · NCT06580314Study of Trastuzumab Deruxtecan Versus Standard of Care Chemotherapy for HER2-Expressing (IHC 3+/2+) Endometrial Cancer
- Avera Medical Group Gynecologic Oncology Sioux Falls, Sioux Falls
- Texas Oncology, P.A. - Tyler, Sioux Falls
RecruitingPhase 3
Ages 18 and older · Women · Updated Jul 28, 2026 · NCT07022483I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer
- Sanford Clinical Research, Sioux Falls
RecruitingPhase 2
Ages 18 and older · All sexes · Updated May 6, 2026 · NCT01042379Avera Cancer Sequencing and Analytics Protocol (ASAP)
- Avera Cancer Institute - Aberdeen, Aberdeen
- Avera Cancer Institute - Mitchell, Mitchell
- Avera Cancer Institute - Pierre, Pierre
- and 2 more
RecruitingObservational study
Ages 18 and older · All sexes · Updated Mar 27, 2026 · NCT05142033Melanoma Margins Trial-II: 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous Melanoma
- Sanford Cancer Center Oncology Clinic, Sioux Falls
- Sanford USD Medical Center - Sioux Falls, Sioux Falls
Recruiting
Ages 18 and older · All sexes · Updated Nov 27, 2024 · NCT03860883From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.