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Liver Cancer (Hepatocellular Carcinoma) clinical trials in Virginia

17 studies for Liver Cancer (Hepatocellular Carcinoma) are looking for participants at sites in Virginia.

Cities in Virginia

The Vanguard Study: Testing a New Way to Screen for Cancer

  • Sentara Martha Jefferson Hospital, Charlottesville
  • Inova Schar Cancer Institute, Fairfax
  • Inova Fair Oaks Hospital, Fairfax
  • and 5 more
RecruitingHealthy volunteers welcome
Ages 45 to 75 · All sexes · Updated Oct 5, 2026 · NCT06995898

Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors

  • Exelixis Clinical Site #66, Charlottesville
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT05176483

Study of the Theranostic Pair RYZ811 (Diagnostic) and RYZ801 (Therapeutic) to Identify and Treat Subjects With GPC3+ (Glypican-3) Unresectable HCC

  • Research Facility, Charlottesville
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT06726161

National Liver Cancer Screening Trial

  • Virginia Commonwealth University, Richmond
RecruitingPhase 4
Ages 18 to 85 · All sexes · Updated Sep 25, 2026 · NCT06084234

A Prospective Study of Memantine in Patients With Cirrhosis and Liver Cancer

  • Inova Schar Cancer Institute, Fairfax
  • Inova Health Care Service, Falls Church
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT06007846

Real-world Evaluation of the HistoSonics Edison System for Treatment of Liver Tumors Across Multidisciplinary Users (BOOMBOX: Master Study)

  • Henrico Doctors' Hospital, Richmond
RecruitingObservational study
Ages 22 and older · All sexes · Updated Sep 11, 2026 · NCT06486454

Phase III Study of Rilvegostomig in Combination With Bevacizumab With or Without Tremelimumab as First-line Treatment of Hepatocellular Carcinoma

  • Research Site, Arlington
  • Research Site, Salem
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT06921785

FOG-001 in Locally Advanced or Metastatic Solid Tumors

  • University of Virginia, Charlottesville
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT05919264

Testing Immunotherapy With or Without Stereotactic Body Radiation Therapy in Patients With Advanced Liver Cancer, HELIO-RT Trial

  • Inova Alexandria Hospital, Alexandria
  • Inova Schar Cancer Institute, Fairfax
  • Inova Fair Oaks Hospital, Fairfax
  • and 2 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT07166406

A Study to Evaluate ARV-6723 Alone and With Pembrolizumab in Participants With Advanced Solid Tumors

  • Clinical Trial Site, Fairfax
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 6, 2026 · NCT07749586

A Study to Evaluate the Efficacy and Safety of Ifinatamab Deruxtecan (I-DXd) in Subjects With Recurrent or Metastatic Solid Tumors (IDeate-PanTumor02)

  • Virginia Cancer Specialists, Fairfax
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT06330064

A Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors

  • NEXT Virginia, Fairfax
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jul 22, 2026 · NCT05208762

A Study to Evaluate ALN-BCAT in Patients With Hepatocellular Carcinoma

  • Clinical Trial Site, Richmond
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 17, 2026 · NCT06600321

DB-1311 in Combination With BNT327 or DB-1305 in Advanced/Metastatic Solid Tumors

  • USA05-0, Virginia Beach
RecruitingPhase 2
Ages 18 and older · All sexes · Updated May 22, 2026 · NCT06953089

A Phase 1/2a Study of DB-1311/BNT324 in Advanced/Metastatic Solid Tumors

  • Research Site 102, Fairfax
  • Research Site 112, Fairfax
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Nov 21, 2025 · NCT05914116

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

  • Massive Bio SYNERGY-AI site, Charlottesville
RecruitingObservational study
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

The Study of Atezolizumab, Bevacizumab and Memantine in Patients With Hepatocellular Carcinoma (HCC)

  • Inova Schar Cancer Institute - Fair Oaks, Fairfax
  • Inova Health Care Service, Falls Church
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 7, 2025 · NCT06789757

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.