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Lung Cancer clinical trials in Louisville, KY

11 studies for Lung Cancer are looking for participants at sites in and around Louisville (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

A Study of ZW251 in Participants With Advanced Solid Tumors

RecruitingPhase 1
  • Norton Cancer Institute, Louisville
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT07164313

Chemotherapy Combined With Immunotherapy Versus Immunotherapy Alone for Older Adults With Stage IIIB-IV Lung Cancer, The ACHIEVE Trial

RecruitingPhase 3
  • The James Graham Brown Cancer Center at University of Louisville, Louisville
  • UofL Health Medical Center Northeast, Louisville
Ages 70 and older · All sexes · Updated Oct 5, 2026 · NCT06096844

Safety and Efficacy of OBX-115 in Advanced Solid Tumors

RecruitingPhase 1/2
  • James Graham Brown Cancer Center (Melanoma/NSCLC), Louisville
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT06060613

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

RecruitingPhase 3
  • Baptist Health Louisville, Louisville
  • Baptist Health Floyd, New Albany · 4 mi away
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT04267848

Study of XmAb®819 in Subjects With Advanced Clear Cell Renal Cell Carcinoma

RecruitingPhase 1
  • Xencor Investigative Site, Louisville
Ages 18 and older · All sexes · Updated Aug 3, 2026 · NCT05433142

Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)

RecruitingPhase 1/2
  • Norton Cancer Institute, Louisville
Ages 18 and older · All sexes · Updated Jul 29, 2026 · NCT04198766

EXoPERT EMERALD Clinical Study

RecruitingObservational studyHealthy volunteers welcome
  • KCTL, Louisville
Ages 45 and older · All sexes · Updated Jul 1, 2026 · NCT07186296

Autologous LN-145 in Patients With Metastatic Non-Small-Cell Lung Cancer

RecruitingPhase 2
  • University of Louisville, Louisville
Ages 18 to 70 · All sexes · Updated Jun 26, 2026 · NCT04614103

cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease

RecruitingObservational studyHealthy volunteers welcome
  • Baptist Floyd, New Albany · 4 mi away
Ages 40 and older · All sexes · Updated Jan 20, 2026 · NCT05366881

Clinical Utility of Management of Patients With Pulmonary Nodules Using the Percepta Nasal Swab Classifier

RecruitingObservational study
  • Robley Rex VA Medical Center, Louisville
Ages 29 to 85 · All sexes · Updated Nov 13, 2024 · NCT06426628

About Lung Cancer

Lung cancer forms in tissues of the lung, usually in the cells that line the air passages. It is the leading cause of cancer death in both men and women.

More about Lung Cancer on MedlinePlus

Lung Cancer trials in other cities

Other studies in Louisville

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.