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Lung Cancer clinical trials in Detroit, MI

20 studies for Lung Cancer are looking for participants at sites in and around Detroit (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

The Vanguard Study: Testing a New Way to Screen for Cancer

RecruitingHealthy volunteers welcome
  • Henry Ford Hospital, Detroit
  • Henry Ford Medical Center - Detroit Northwest, Detroit
Ages 45 to 75 · All sexes · Updated Oct 5, 2026 · NCT06995898

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

RecruitingPhase 3
  • Henry Ford Hospital, Detroit
  • Henry Ford Health Saint John Hospital, Detroit
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT04267848

Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancer

RecruitingPhase 3
  • Henry Ford Health Saint John Hospital, Detroit
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT04181060

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Henry Ford Hospital, Detroit
  • Henry Ford Health Saint John Hospital, Detroit
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial

RecruitingPhase 3
  • Henry Ford Hospital, Detroit
  • Henry Ford Health Saint John Hospital, Detroit
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06498635

Study of Daraxonrasib (RMC-6236) in Patients With RAS Mutated NSCLC (RASolve 301)

RecruitingPhase 3
  • Karmanos Cancer Institute, Detroit
  • Henry Ford Health, Detroit
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT06881784

Open Label Study to Evaluate BL-M07D1 in HER2 Expressing Malignant Solid Tumors

RecruitingPhase 1
  • Karmanos Cancer Institiute, Detroit
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT06293898

Open-label Study of BBO-8520 in Adult Subjects With KRASG12C Non-small Cell Lung Cancer

RecruitingPhase 1
  • Henry Ford Cancer - Detroit, Detroit
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT06343402

Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer

RecruitingPhase 3
  • Wayne State University/Karmanos Cancer Institute, Detroit
  • Henry Ford Hospital, Detroit
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT05624996

Testing Proton Craniospinal Radiation Therapy Versus the Usual Radiation Therapy for Leptomeningeal Metastasis, RADIATE-LM Trial

RecruitingPhase 3
  • Wayne State University/Karmanos Cancer Institute, Detroit
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT06500481

A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors

RecruitingPhase 1/2
  • Karmanos Cancer Institute, Detroit
Ages 18 and older · All sexes · Updated Aug 11, 2026 · NCT05592626

Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)

RecruitingPhase 1/2
  • Henry Ford Cancer Institute, Detroit
Ages 18 and older · All sexes · Updated Jul 29, 2026 · NCT04198766

Study of Sacituzumab Govitecan With Atezolizumab/Durvalumab as Maintenance Therapy for Extensive-Stage Small Cell Lung Cancer

RecruitingPhase 2
  • Henry Ford Cancer- Detroit, Detroit
Ages 18 and older · All sexes · Updated Jul 28, 2026 · NCT07339059

Study of RAS(ON) Inhibitors in Patients With Advanced RAS-mutated NSCLC

RecruitingPhase 1/2
  • Henry Ford Cancer - Detroit (Brigitte Harris Cancer Pavilion), Detroit
Ages 18 and older · All sexes · Updated Jun 30, 2026 · NCT06162221

Autologous LN-145 in Patients With Metastatic Non-Small-Cell Lung Cancer

RecruitingPhase 2
  • Karmanos Cancer Institute, Detroit
Ages 18 to 70 · All sexes · Updated Jun 26, 2026 · NCT04614103

Comparing Combinations of Targeted Drugs for Advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes (A Lung-MAP Treatment Trial)

RecruitingPhase 2
  • Henry Ford Hospital, Detroit
Ages 18 and older · All sexes · Updated Jun 3, 2026 · NCT05642572

A Study Evaluating FMC-376 in Participants With KRAS G12C Mutated Solid Tumors

RecruitingPhase 1/2
  • Karmanos Cancer Institute, Detroit
Ages 18 and older · All sexes · Updated Mar 18, 2026 · NCT06244771

A Study Assessing KB707 for the Treatment of Advanced Solid Tumor Malignancies Affecting the Lungs

RecruitingPhase 1/2
  • Henry Ford Health, Detroit
Ages 18 and older · All sexes · Updated Oct 24, 2025 · NCT06228326

About Lung Cancer

Lung cancer forms in tissues of the lung, usually in the cells that line the air passages. It is the leading cause of cancer death in both men and women.

More about Lung Cancer on MedlinePlus

Lung Cancer trials in other cities

Other studies in Detroit

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.