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Ensaios clínicos de Câncer Metastático em Pensilvânia

68 estudos para Câncer Metastático estão buscando participantes em locais em Pensilvânia.

Cidades em Pensilvânia

Texto oficial do estudo (Inglês)

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

  • Lehigh Valley Hospital-Cedar Crest, Allentown
  • UPMC Altoona, Altoona
  • Lehigh Valley Hospital - Muhlenberg, Bethlehem
  • e mais 18
RecrutandoFase 2
Todas as idades · Todos os sexos · Atualizado em 2 de out. de 2026 · NCT05564377

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

  • Abramson Cancer Center of the University of Pennsylvania, Philadelphia
  • University of Pittsburgh Medical Center, Pittsburgh
  • WellSpan York Cancer Center, York
RecrutandoFase 1/2
Idades 12 e acima · Todos os sexos · Atualizado em 2 de out. de 2026 · NCT04585750

Atebimetinib + GnP as a First Line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma

  • Thomas Jefferson University, Philadelphia
RecrutandoFase 3
Idades 18 e acima · Todos os sexos · Atualizado em 2 de out. de 2026 · NCT07562152

Testing the Safety and Tolerability of the Anti-cancer Drugs Trastuzumab Deruxtecan and Neratinib for Cancers With Changes in the HER2 Gene

  • UPMC Hillman Cancer Center, Pittsburgh
RecrutandoFase 1
Idades 18 e acima · Todos os sexos · Atualizado em 2 de out. de 2026 · NCT05372614

A Study With NKT3964 for Adults With Advanced/Metastatic Solid Tumors

  • Sidney Kimmell Cancer Center - Jefferson Health, Philadelphia
RecrutandoFase 1
Idades 19 e acima · Todos os sexos · Atualizado em 1 de out. de 2026 · NCT06586957

A Study to Assess the Safety, Tolerability, Pharmacokinetic, Pharmacodynamic, Immunogenicity and Antitumour Activity of IPN60300 in Adults With Locally Advanced or Metastatic Solid Tumours

  • Sidney Kimmel Cancer Center, Philadelphia
RecrutandoFase 1/2
Idades 18 e acima · Todos os sexos · Atualizado em 1 de out. de 2026 · NCT07213817

Zanzalintinib Versus Everolimus in Participants With Locally Advanced or Metastatic Neuroendocrine Tumors

  • University of Pennsylvania, Philadelphia
  • University of Pittsburgh Medical Center (UPMC) Hillman Cancer Center, Pittsburgh
RecrutandoFase 2/3
Idades 18 e acima · Todos os sexos · Atualizado em 29 de set. de 2026 · NCT06943755

Testing the Addition of an Anti-Cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment (Capecitabine) for Metastatic or Unresectable Cancers

  • UPMC Hillman Cancer Center, Pittsburgh
RecrutandoFase 1
Idades 18 e acima · Todos os sexos · Atualizado em 29 de set. de 2026 · NCT05803382

A Study of IDE892 as Monotherapy and Combination in MTAP-deleted Advanced Solid Tumors

  • Sidney Kimmel Comprehensive Cancer Center Thomas Jefferson University, Philadelphia
RecrutandoFase 1
Idades 18 e acima · Todos os sexos · Atualizado em 28 de set. de 2026 · NCT07277413

A Study of Repotrectinib in Pediatric and Young Adult Subjects Harboring ALK, ROS1, OR NTRK1-3 Alterations

  • Children's Hospital of Philadelphia-Center for Childhood Cancer Research, Philadelphia
RecrutandoFase 1/2
Até 25 anos · Todos os sexos · Atualizado em 25 de set. de 2026 · NCT04094610

A Study of Zidesamtinib (NVL-520) in Patients With Advanced NSCLC and Other Solid Tumors Harboring ROS1 Rearrangement (ARROS-1)

  • Fox Chase Cancer Center, Philadelphia
RecrutandoFase 1/2
Idades 12 e acima · Todos os sexos · Atualizado em 24 de set. de 2026 · NCT05118789

A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract

  • Lancaster General Hospital - Ann B Barshinger Cancer Institute, Lancaster
  • AHN Allegheny General Hospital, Pittsburgh
RecrutandoFase 3
Idades 18 e acima · Todos os sexos · Atualizado em 22 de set. de 2026 · NCT07218380

Prospective External Control Cohort In Patients With Newly Diagnosed Advanced or Metastatic EGFR Mutant Non-Small Cell Lung Cancer

  • Lankenau Medical Center, Paoli
RecrutandoEstudo observacional
Idades 18 e acima · Todos os sexos · Atualizado em 22 de set. de 2026 · NCT07028489

A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)

  • St. Luke's University Health Network, Bethlehem
  • Lancaster General Hospital - Ann B Barshinger Cancer Institute, Lancaster
  • University of Pennsylvania Hospital, Philadelphia
  • e mais 3
RecrutandoFase 3
Idades 18 e acima · Todos os sexos · Atualizado em 22 de set. de 2026 · NCT07174336

Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

  • Allegheny Health Network, Pittsburgh
RecrutandoFase 1/2
Idades 18 e acima · Todos os sexos · Atualizado em 22 de set. de 2026 · NCT06128551

A Study of LY4257496 in Participants With Cancer (OMNIRAY)

  • University of Pittsburgh Medical Center, Pittsburgh
RecrutandoFase 1
Idades 18 e acima · Todos os sexos · Atualizado em 22 de set. de 2026 · NCT07114601

SLV-154 Treatment of Advanced Cancers

  • Fox Chase Cancer Center, Philadelphia
RecrutandoFase 1
Idades 12 e acima · Todos os sexos · Atualizado em 22 de set. de 2026 · NCT06771219

A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Parts B and C) Ovarian Cancer

  • University of Pennsylvania Hospital, Philadelphia
  • Jefferson Health Honickman Center, Philadelphia
  • Asplundh Cancer Pavilion, Willow Grove
RecrutandoFase 3
Idades 18 e acima · Todos os sexos · Atualizado em 22 de set. de 2026 · NCT07213804

A Study of Nuzefatide Pevedotin (BT5528) in Patients With Metastatic Pancreatic Ductal Adenocarcinoma (PDAC)

  • Thomas Jefferson University, Sidney Kimmel Comprensive Cancer Center, Clinical Trials Office, Philadelphia
RecrutandoFase 2
Idades 18 e acima · Todos os sexos · Atualizado em 18 de set. de 2026 · NCT07450859

A Clinical Study of Ifinatamab Deruxtecan Based Treatment Combinations or as Monotherapy to Treat Metastatic Castrate Resistant Prostate Cancer (mCRPC) (MK-2400-01A/IDeate-Prostate02)

  • UPMC Hillman Cancer Center ( Site 0014), Pittsburgh
RecrutandoFase 1/2
Idades 18 e acima · Todos os sexos · Atualizado em 17 de set. de 2026 · NCT06863272

Study of ISM6331 in Participants With Advanced/Metastatic Mesothelioma or Other Advanced Solid Tumors

  • University of Pennsylvania - Abramson Cancer Center, Philadelphia
RecrutandoFase 1/2
Idades 18 e acima · Todos os sexos · Atualizado em 16 de set. de 2026 · NCT06566079

CR-001 in Adult Participants With Locally Advanced or Metastatic Solid Tumors

  • Clinical Study Site, Pittsburgh
RecrutandoFase 1/2
Idades 18 e acima · Todos os sexos · Atualizado em 10 de set. de 2026 · NCT07335497

Testing the Combination of DS-8201a and Olaparib in HER2-Expressing Cancers With Expansion in Patients With Platinum Resistant Ovarian Cancer

  • UPMC Hillman Cancer Center, Pittsburgh
RecrutandoFase 1
Idades 18 e acima · Todos os sexos · Atualizado em 8 de set. de 2026 · NCT04585958

A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

  • USO - Alliance Cancer Specialists, PC, Horsham
  • Thomas Jefferson University, Sidney Kimmel Cancer Center - Clinical Trials Office, Philadelphia
  • UPMC Hillman Cancer Center, Pittsburgh
RecrutandoFase 3
Idades 18 e acima · Todos os sexos · Atualizado em 8 de set. de 2026 · NCT06119581

AVENTINE-1: Study of AVZO-1418 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Solid Tumors (AVZO-1418-1001)

  • Avenzo Therapeutics Recruiting Site, Philadelphia
RecrutandoFase 1/2
Idades de 18 a 75 · Todos os sexos · Atualizado em 4 de set. de 2026 · NCT07038343

A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Participants With Breast Cancer

  • Thomas Jefferson University Hospital, Philadelphia
RecrutandoFase 1/2
Idades 18 e acima · Mulheres · Atualizado em 3 de set. de 2026 · NCT04802759

A Study With NKT5097 for Adults With Advanced/Metastatic Solid Tumors

  • UPMC Hillman Cancer Center, Pittsburgh
RecrutandoFase 1
Idades 18 e acima · Todos os sexos · Atualizado em 28 de ago. de 2026 · NCT07029399

A Study of BGB-B455 in Adults With Advanced or Metastatic Solid Tumors

  • Sidney Kimmel Cancer Center, Philadelphia
RecrutandoFase 1
Idades 18 e acima · Todos os sexos · Atualizado em 24 de ago. de 2026 · NCT06803680

A Study to See if Giving Fianlimab and Cemiplimab Together is Better Than Cemiplimab Alone at Treating Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

  • Asplundh Cancer Pavilion, Willow Grove
RecrutandoFase 2
Idades 18 e acima · Todos os sexos · Atualizado em 21 de ago. de 2026 · NCT06769698

FORAGER-1: A Study of Vepugratinib (LY3866288; LOXO-435) in Participants With Cancer With a Change in a Gene Called FGFR3

  • Penn Medicine Lancaster General Hospital - Ann B. Barshinger Cancer Institute, Lancaster
  • University of Pennsylvania, Philadelphia
  • Thomas Jefferson University, Philadelphia
  • e mais 2
RecrutandoFase 1
Idades 18 e acima · Todos os sexos · Atualizado em 20 de ago. de 2026 · NCT05614739

Pemefolacianine for IMI of Lung Cancer

  • University of Pennsylvania, Philadelphia
RecrutandoFase 1
Idades 18 e acima · Todos os sexos · Atualizado em 19 de ago. de 2026 · NCT07772895

FOG-001 in Locally Advanced or Metastatic Solid Tumors

  • University of Pennsylvania, Perelman School of Medicine, Philadelphia
  • University of Pittsburgh Medical Center, Hillman Cancer Center, Pittsburgh
RecrutandoFase 1/2
Idades 18 e acima · Todos os sexos · Atualizado em 17 de ago. de 2026 · NCT05919264

Testing the Combination of the Anti-Cancer Drugs Temozolomide and M1774 to Evaluate Their Safety and Effectiveness

  • UPMC Hillman Cancer Center, Pittsburgh
RecrutandoFase 1/2
Idades 18 e acima · Todos os sexos · Atualizado em 31 de jul. de 2026 · NCT05691491

A Study to Investigate Safety and Effectiveness of CRN09682 in Participants With SST2-Expressing NENs and Other Solid Tumors

  • Crinetics Study Site, Philadelphia
  • Crinetics Study Site, Philadelphia
RecrutandoFase 1/2
Idades 18 e acima · Todos os sexos · Atualizado em 31 de jul. de 2026 · NCT07129252

A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors

  • University of Pennsylvania / Abramson Cancer Center, Philadelphia
  • Thomas Jefferson University, Sidney Kimmel Cancer Center, Clinical Research Organization, Philadelphia
RecrutandoFase 1/2
Idades 18 e acima · Todos os sexos · Atualizado em 30 de jul. de 2026 · NCT04657068

Puxitatug Samrotecan (AZD8205) Monotherapy vs Chemotherapy in B7-H4-selected Endometrial Cancer (Bluestar-Endometrial01)

  • Research Site, Bethlehem
  • Research Site, Hershey
  • Research Site, Lancaster
  • e mais 5
RecrutandoFase 3
Idades 18 e acima · Mulheres · Atualizado em 29 de jul. de 2026 · NCT07044336

Study of Orally Administered MOMA-313 in Participants With Advanced or Metastatic Solid Tumors

  • Investigative Site #109, Philadelphia
RecrutandoFase 1
Idades 18 e acima · Todos os sexos · Atualizado em 23 de jul. de 2026 · NCT06545942

A Study of CHS-114 (Tagmokitug) in Combination With Toripalimab and/or Other Treatments in Participants With Advanced Solid Tumors

  • University of Pittsburg Medical Center _UPMC Hillman Cancer Center, Pittsburgh
RecrutandoFase 1
Idades 18 e acima · Todos os sexos · Atualizado em 15 de jul. de 2026 · NCT06657144

A Study of PYX-201 in Advanced Solid Tumors

  • University of Pennsylvania, Abramson Cancer Center, Philadelphia
RecrutandoFase 1
Idades 18 e acima · Todos os sexos · Atualizado em 30 de jun. de 2026 · NCT05720117

Fonte: ClinicalTrials.gov, dados obtidos em 5 de out. de 2026. Cada estudo define seus próprios critérios de elegibilidade; a equipe do estudo decide quem pode participar.