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Kliničke studije za Плоскоклеточни карцином главе и врата u državi Пенсилванија

42 studija za Плоскоклеточни карцином главе и врата traži učesnike na lokacijama u državi Пенсилванија.

Gradovi u državi Пенсилванија

Zvanični tekst studije (na engleskom)

Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma

  • UPMC Altoona, Altoona
  • Geisinger Medical Center, Danville
  • UPMC Hillman Cancer Center Erie, Erie
  • и још 12
Тражи се учесникФаза 2
Узраст од 18 до 79 · Оба пола · Ажурирано 12. 11. 2026. · NCT04671667

Testing the Addition of Anti-Cancer Drug, Cetuximab, to Standard of Care Treatment (Pembrolizumab) for Returning or Spreading Head and Neck Cancer After Previous Treatment

  • Lehigh Valley Hospital-Cedar Crest, Allentown
  • Lehigh Valley Hospital - Muhlenberg, Bethlehem
  • Carlisle Regional Cancer Center, Carlisle
  • и још 15
Тражи се учесникФаза 3
Узраст 18 и старији · Оба пола · Ажурирано 12. 11. 2026. · NCT06589804

Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)

  • Lehigh Valley Health Network, Allentown
Тражи се учесникФаза 1/2
Узраст 18 и старији · Оба пола · Ажурирано 6. 11. 2026. · NCT04198766

High-dose Prophylactic Gabapentin (HOPE) vs. Placebo to Prevent Opioid Use for Oral Mucositis Pain During Concurrent Chemoradiation for Head and Neck Cancer

  • Geisinger Medical Center, Danville
  • Geisinger Cancer Center Dickson City, Dickson City
  • UPMC Hillman Cancer Center Erie, Erie
  • и још 21
Тражи се учесникФаза 3
Узраст 18 и старији · Оба пола · Ажурирано 4. 11. 2026. · NCT06992427

VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma

  • Cancer Care Associates of York (site 206), York
Тражи се учесникФаза 1/2
Узраст од 18 до 80 · Оба пола · Ажурирано 4. 11. 2026. · NCT03556228

A Study of JNJ-90301900 in Combination With Chemoradiation Therapy in Participants With Locally Advanced Head and Neck Squamous Cell Carcinoma

  • University of Pennsylvania, Philadelphia
Тражи се учесникФаза 1
Узраст од 18 до 74 · Оба пола · Ажурирано 3. 11. 2026. · NCT07219212

A Study of Amivantamab in Addition to Standard of Care Agents (SOC) Compared With SOC Alone in Participants With Recurrent/Metastatic Head and Neck Cancer

  • Penn State Milton S. Hershey Medical Center, Hershey
  • University of Pennsylvania Perelman Center for Advanced Medicine, Philadelphia
  • Fox Chase Cancer Center, Philadelphia
Тражи се учесникФаза 3
Узраст 18 и старији · Оба пола · Ажурирано 3. 11. 2026. · NCT07276399

JNJ-90301900 (NBTXR3) Activated by Radiotherapy With or Without Cetuximab in LA-HNSCC

  • University of Pennsylvania Perelman Center for Advanced Medicine, Philadelphia
Тражи се учесникФаза 3
Узраст 60 и старији · Оба пола · Ажурирано 3. 11. 2026. · NCT04892173

A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors

  • University of Pennsylvania, Philadelphia
Тражи се учесникФаза 1/2
Узраст 18 и старији · Оба пола · Ажурирано 2. 11. 2026. · NCT03526835

FORTIFI-HN01: A Study of Ficerafusp Alfa (BCA101) or Placebo in Combination With Pembrolizumab in First-Line PD-L1-pos, R or M HNSCC

  • UPMC Hillman Cancer Center (Site #0103), Pittsburgh
  • VA Pittsburgh Healthcare System (Site #0123), Pittsburgh
Тражи се учесникФаза 2/3
Узраст 18 и старији · Оба пола · Ажурирано 29. 10. 2026. · NCT06788990

Testing the Addition of an Anti-Cancer Drug, Camonsertib, to Radiation Therapy for Recurrent Head and Neck Squamous Cell Carcinoma

  • UPMC Hillman Cancer Center, Pittsburgh
Тражи се учесникФаза 1
Узраст 18 и старији · Оба пола · Ажурирано 29. 10. 2026. · NCT07156227

Ordastobart (INBRX-106) Add-on to Pembrolizumab in 1L HPV+ PD-L1+ R/M OPSCC (HexAgon-HN)

  • UPMC Hillman Cancer Center, Pittsburgh
Тражи се учесникФаза 2/3
Узраст 18 и старији · Оба пола · Ажурирано 28. 10. 2026. · NCT06295731

Testing Whether Cemiplimab (REGN2810) Plus CDX-1140 Given Prior to Surgery Are Better Than Cemiplimab (REGN2810) Alone in Patients With Stage III-IV Head and Neck Cancer

  • UPMC Hillman Cancer Center, Pittsburgh
Тражи се учесникФаза 2
Узраст 18 и старији · Оба пола · Ажурирано 26. 10. 2026. · NCT06980038

A Study to See if Giving Fianlimab and Cemiplimab Together is Better Than Cemiplimab Alone at Treating Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

  • Asplundh Cancer Pavilion, Willow Grove
Тражи се учесникФаза 2
Узраст 18 и старији · Оба пола · Ажурирано 22. 10. 2026. · NCT06769698

Window of Opportunity in Preserving Laryngeal Function Trial

  • UPMC Hillman Cancer, Pittsburgh
Тражи се учесникФаза 2
Узраст 18 и старији · Оба пола · Ажурирано 16. 10. 2026. · NCT07423078

A Study to Evaluate CRB-701 Compared to Investigator's Choice Therapy in Previously Treated Oropharyngeal Squamous Cell Carcinoma

  • Penn-Medicine - Abramson Cancer Center University of Pennsylvania, Philadelphia
  • Fox Chase Cancer Center, Philadelphia
Тражи се учесникФаза 3
Узраст 18 и старији · Оба пола · Ажурирано 8. 10. 2026. · NCT07768189

A Study to Investigate Safety of AZD6750 in Adult Participants With Select Advanced or Metastatic Solid Tumors

  • Research Site, Pittsburgh
Тражи се учесникФаза 1/2
Узраст 18 и старији · Оба пола · Ажурирано 8. 10. 2026. · NCT07115043

Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors

  • UPMC Hillman Cancer Center, Pittsburgh
Тражи се учесникФаза 1
Узраст 18 и старији · Оба пола · Ажурирано 6. 10. 2026. · NCT04429542

Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors

  • Exelixis Clinical Site #104, Hershey
  • Exelixis Clinical Site #98, Philadelphia
  • Exelixis Clinical Site #32, Pittsburgh
Тражи се учесникФаза 1
Узраст 18 и старији · Оба пола · Ажурирано 1. 10. 2026. · NCT05176483

A Study of NT-175 in Adult Participants With Advanced Malignancies That Are Positive for HLA-A*02:01 and the TP53 R175H Mutation

  • Research Site, Pittsburgh
Тражи се учесникФаза 1
Узраст 18 и старији · Оба пола · Ажурирано 29. 9. 2026. · NCT05877599

Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery

  • Lehigh Valley Hospital-Cedar Crest, Allentown
  • UPMC Altoona, Altoona
  • UPMC-Heritage Valley Health System Beaver, Beaver
  • и још 27
Тражи се учесникФаза 2
Узраст 18 и старији · Оба пола · Ажурирано 14. 9. 2026. · NCT02734537

ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation

  • University of Pennsylvania, Philadelphia
  • WellSpan Medical Oncology & Hematology at York Cancer Center, York
Тражи се учесникОпсервациона студија
Узраст 18 и старији · Оба пола · Ажурирано 14. 9. 2026. · NCT05059444

Study of Volrustomig as Monotherapy or in Combination With Anti- Cancer Agents in Participants With Advanced/Metastatic Solid Tumors

  • Research Site, Philadelphia
Тражи се учесникФаза 2
Узраст 18 и старији · Оба пола · Ажурирано 11. 9. 2026. · NCT06535607

A Longitudinal Multi-Omic Biomarker Profiling Study of Patients With Head & Neck Squamous Cell Carcinoma (HNSCC)

  • University of Pennsylvania, Philadelphia
  • Cancer Care Associates of York, York
Тражи се учесникОпсервациона студија
Узраст 18 и старији · Оба пола · Ажурирано 3. 9. 2026. · NCT06163534

FT836 With or Without Chemotherapy and/or Monoclonal Antibodies, in Participants With Advanced Solid Tumors

  • Thomas Jefferson University, Sidney Kimmel Cancer Center, Philadelphia
Тражи се учесникФаза 1
Узраст 18 и старији · Оба пола · Ажурирано 2. 9. 2026. · NCT07216105

A Phase 1 Study of NRM-823 in Participants With Locally Advanced or Metastatic Refractory Solid Tumors

  • Normunity Investigational Site, Philadelphia
  • Normunity Investigational Site, Philadelphia
Тражи се учесникФаза 1
Узраст 18 и старији · Оба пола · Ажурирано 18. 8. 2026. · NCT07182149

Comparing Sentinel Lymph Node (SLN) Biopsy With Standard Neck Dissection for Patients With Early-Stage Oral Cavity Cancer

  • Carlisle Regional Cancer Center, Carlisle
  • Geisinger Medical Center, Danville
  • UPMC Hillman Cancer Center Erie, Erie
  • и још 9
Тражи се учесникФаза 2/3
Узраст 18 и старији · Оба пола · Ажурирано 17. 8. 2026. · NCT04333537

Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer

  • Chambersburg Hospital, Chambersburg
  • Ephrata Cancer Center, Ephrata
  • UPMC Hillman Cancer Center Erie, Erie
  • и још 16
Тражи се учесникФаза 2
Узраст 18 и старији · Оба пола · Ажурирано 17. 8. 2026. · NCT06532279

Anti-PD-1 mAb Plus Metabolic Modulator in Solid Tumor Malignancies

  • UPMC Hillman Cancer Center, Pittsburgh
Тражи се учесникФаза 2
Узраст 18 и старији · Оба пола · Ажурирано 23. 6. 2026. · NCT04114136

Study With ABBV-CLS-484 in Participants With Locally Advanced or Metastatic Tumors

  • Perelman Center for Advanced Medicine /ID# 250188, Philadelphia
  • UPMC Hillman Cancer Ctr /ID# 225706, Pittsburgh
Тражи се учесникФаза 1
Узраст 18 и старији · Оба пола · Ажурирано 4. 6. 2026. · NCT04777994

A Study of Dostarlimab vs Placebo After Chemoradiation in Adult Participants With Locally Advanced Unresected Head and Neck Squamous Cell Carcinoma

  • GSK Investigational Site, Philadelphia
  • GSK Investigational Site, Pittsburgh
Тражи се учесникФаза 3
Узраст 18 и старији · Оба пола · Ажурирано 26. 5. 2026. · NCT06256588

Intratumoral Lidocaine Injection Before Oropharyngeal Cancer Surgery

  • Abramson Cancer Center at University of Pennsylvania, Philadelphia
Тражи се учесникФаза 1
Узраст 18 и старији · Оба пола · Ажурирано 12. 5. 2026. · NCT06747390

Neoadjuvant CADI-05 in Combination With Pembrolizumab for Surgically Resectable Locally Advanced Head and Neck Squamous Cell Carcinomas

  • Fox Chase Cancer Center, Philadelphia
  • Temple University Hospital, Philadelphia
Тражи се учесникФаза 1
Узраст 18 и старији · Оба пола · Ажурирано 15. 4. 2026. · NCT07455032

A Study of Ficlatuzumab in Combination With Cetuximab in Participants With Recurrent or Metastatic (R/M) HPV Negative Head and Neck Squamous Cell Carcinoma

  • Fox Chase Cancer Center, Philadelphia
  • University of Pittsburgh Medical Center - Hillman Cancer Center, Pittsburgh
Тражи се учесникФаза 3
Узраст 18 и старији · Оба пола · Ажурирано 9. 4. 2026. · NCT06064877

A Study of VET3-TGI in Patients With Solid Tumors

  • UPMC- Hillman Cancer Center, Pittsburgh
Тражи се учесникФаза 1
Узраст 18 и старији · Оба пола · Ажурирано 7. 4. 2026. · NCT06444815

Study of CP-383 in Patients With Advanced or Metastatic Solid Tumors

  • University of Pennsylvania, Philadelphia
Тражи се учесникФаза 1/2
Узраст 18 и старији · Оба пола · Ажурирано 18. 2. 2026. · NCT07030257

Virtual Reality 3D-Surgery Modeling to Enhance Head and Neck Cancer Surgery Quality

  • Sidney Kimmel Cancer Center at Thomas Jefferson University, Philadelphia
Тражи се учесник
Узраст 18 и старији · Оба пола · Ажурирано 17. 2. 2026. · NCT05031910

A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation

  • Thomas Jefferson University, Sidney Kimmel Cancer Center, Philadelphia
  • Fox Chase Cancer Center, Philadelphia
Тражи се учесникФаза 1
Узраст 18 и старији · Оба пола · Ажурирано 13. 2. 2026. · NCT06778863

Use of SPY Imaging System to Minimize Fistulas After Hypopharyngeal Reconstruction

  • UPMC, Pittsburgh
Тражи се учесникФаза 2
Узраст 18 и старији · Оба пола · Ажурирано 9. 1. 2026. · NCT06831149

A Study of ASP-1929 Photoimmunotherapy in Combination With Pembrolizumab in First-line Treatment of Locoregional Recurrent Squamous Cell Carcinoma of the Head and Neck With No Distant Metastases

  • Thomas Jefferson University, Sidney Kimmel Cancer Center, Philadelphia
Тражи се учесникФаза 3
Узраст 18 и старији · Оба пола · Ажурирано 15. 10. 2025. · NCT06699212

Sa sajta ClinicalTrials.gov, podaci preuzeti 15. 11. 2026.. Svaka studija ima svoje kriterijume za uključivanje; tim studije odlučuje ko može da učestvuje.