Home › Obstructive Sleep Apnea › NCT00695214

Drug-Induced Sleep Endoscopy for Upper Airway Evaluation in Obstructive Sleep Apnea

Who can join

Ages 18 and older · All sexes

Inclusion Criteria:

* Adult patients with OSA considering surgical treatment

Exclusion Criteria:

* Minors
* Pregnant women
* Patients unable to provide informed consent in English themselves
* Prisoners
* Allergy to propofol, soybean oil, egg lecithin or glycerol
* Other contraindication to use of propofol (decision of anesthesiologist or otolaryngologist.)

About the study

Prospective, interventional cohort study of drug-induced sleep endoscopy (DISE) to evaluate the upper airway in a cohort of obstructive sleep apnea (OSA) surgical patients. This study has investigated the reliability of this technique, demonstrating moderate-substantial interrater and test-retest reliability. This research has also compared DISE findings to those of the lateral cephalogram X-ray and examined DISE findings in individuals who have not responded to previous sleep apnea surgery. These papers have been published and available through PubMed. Additional research is ongoing, with examination of DISE findings, comparison to other evaluation techniques, and the association between DISE findings and surgical outcomes.

What is being tested

• Propofol sedation (drug)

Sponsor: University of California, Los Angeles · Participants: 800 · Started: 2004-02

Contact the study team

• Eric J Kezirian, MD, MPH · Phone: 4242596559

Official record on ClinicalTrials.gov — NCT00695214

Locations in the U.S.

Conditions

• Obstructive Sleep Apnea

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.