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Pancreatic Adenocarcinoma Gene Environment Risk Study

RecruitingObservational studyHealthy volunteers welcome

The Pancreatic Adenocarcinoma Gene Environment Risk Study -A Prospective Cohort Study of Patients at Risk or Having Pancreatic Disease

Who can join

Ages 18 and older · All sexes · Healthy volunteers welcome

Full eligibility criteria
Inclusion Criteria:

* Histologically confirmed or CT confirmed diagnosis of pancreatic adenocarcinoma
* Subjects with abnormal imaging study (CT, MRI, MRCP, EUS)
* Control subjects with a clinical diagnosis of a pancreas, liver, or intestinal condition
* Control subject with acute pancreatitis
* Control subject with chronic pancreatitis
* Control subject with biliary obstruction
* Control subject with pancreatic cyst
* Member of a high risk family (≥ 1 close relative with pancreatic cancer)
* Healthy control (without any of the above conditions)

Exclusion Criteria:

* Under the age of 18 years
* Unable to give informed consent
* Inability to travel to Pittsburgh for in-person enrollment

About the study

After informed consent, participants will be asked to complete a medical/family history questionnaire and provide a blood sample. Some participants may also be asked to provide a urine sample. Individuals undergoing procedures that require collection of biological samples for clinical purposes may have these samples saved for research purposes. Participants will also be asked for their permission for study investigators to access medical records and/or recontact them for updates to their medical and family histories. Data and biospecimens will be stored for potential future research projects.

Sponsor: University of Pittsburgh · Participants: 10,000 · Started: 2004-01

Contact the study team

Official record on ClinicalTrials.gov — NCT00912717

Locations in the U.S.

PennsylvaniaUniversity of Pittsburgh, Pittsburgh

Conditions

From ClinicalTrials.gov, data retrieved Oct 2, 2026. Each study sets its own eligibility; the study team decides who can join.