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Pancreatic Cancer Genetics

RecruitingObservational study

Molecular Genetics and Epidemiology of Pancreatic Cancer in Ashkenazi Jewish Patients

Who can join

Ages 18 to 85 · All sexes

Full eligibility criteria
Inclusion Criteria:

* Patients diagnosed with pancreatic cancer.
* Patients are of Ashkenazi Jewish descent.
* Patients have been Columbia Pancreatic Cancer Prevention Program Registry and Tissue Bank for High-Risk Individuals (IRB-AAAA6154).

Exclusion Criteria:

* Inability to provide informed consent.
* Under the age of 18 years old.

About the study

The aim of this study is to determine the frequency of the three most common BReast CAncer gene 1 (BRCA1) and BReast CAncer gene 2 (BRCA2) genetic mutations that are commonly found in Ashkenazi Jewish patients with pancreatic cancer. Testing for BRCA1 and BRCA2 mutations in relatives of hereditary pancreatic cancer patients may have a significant impact; allowing for early screening, treatment, and resection of pre-malignant tissue or malignant lesions.

Sponsor: Columbia University · Participants: 100 · Started: 2008-01

Contact the study team

Official record on ClinicalTrials.gov — NCT01102569

Locations in the U.S.

New YorkColumbia University Medical Center, New York

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.