Home › Diffuse Intrinsic Pontine Glioma › NCT01106794

Molecular Analysis of Samples From Patients With Diffuse Intrinsic Pontine Glioma and Brainstem Glioma

Who can join

Up to age 21 · All sexes

Inclusion Criteria:

* Patients of any age with clinical and radiologic diagnosis of diffuse intrinsic pontine glioma
* Patients with other high-grade gliomas originating in the brainstem
* Patients with focal gliomas (WHO grade I/II) of the brainstem

Exclusion Criteria:

* Patients with any type of infiltrative low grade (WHO grade I and II) or high grade glioma (WHO grade III and IV) originating outside the brainstem
* Patients harboring primary brainstem tumors with other histologic diagnoses (e.g., PNET)

About the study

The purpose of this study is to prospectively collect specimens from pediatric patients with diffuse intrinsic pontine glioma or brainstem glioma, either during therapy or at autopsy, in order to characterize the molecular abnormalities of this tumor.

Sponsor: Children's National Research Institute · Participants: 100 · Started: 2010-04

Contact the study team

• Javad Nazarian, PhD · Phone: 202-476-6022
• Caroline Kopsidas, BS · Phone: 240-393-3359

Official record on ClinicalTrials.gov — NCT01106794

Locations in the U.S.

Conditions

• Diffuse Intrinsic Pontine Glioma

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.