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Optical Coherence Tomography Guided Transepithelial Phototherapeutic Keratectomy

Who can join

Ages 18 and older · All sexes

Inclusion Criteria:

* Patients with vision primarily limited by superficial opacities and irregularities that could be removed by PTK while leaving at least 250 µm.

Exclusion Criteria:

* Inability to give informed consent
* Inability to maintain stable fixation for OCT imaging
* Inability to commit to required visits to complete the study
* Deep corneal opacities and irregularities
* Cataracts, retinal disease, glaucoma, or other eye conditions that may limit the visual outcome after surgery

About the study

Optical Coherence Tomography (OCT) machines are non-contact instruments that can measure the depth of scars and other causes of cloudiness in the front of the cornea. The purpose of this study is to determine whether OCT-guided settings for the lasers used for removal of corneal scars and other partial-thickness corneal defects result in improved vision in patients receiving these procedures.

What is being tested

• OCT-guided laser phototherapeutic keratectomy (drug)

Sponsor: Oregon Health and Science University · Participants: 80 · Started: 2011-06

Contact the study team

• Humberto Martinez, COT · Phone: 503-494-7712
• Denny Romfh, OD · Phone: 503-494-4351

Official record on ClinicalTrials.gov — NCT01243931

Locations in the U.S.

From ClinicalTrials.gov, data retrieved Oct 3, 2026. Each study sets its own eligibility; the study team decides who can join.