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Cryopreservation of Ovarian Tissue
Recruiting
Cryopreservation of Ovarian Tissue for Potential In Vitro Maturation or Autologous Transplantation
Who can join
Up to age 45 · Women
Full eligibility criteria
Inclusion Criteria: * Females 0-45 years of age who are premenopausal * Treatment plan that will likely result in premature menopause or premature ovarian failure * This includes patients receiving: * Cancer treatment with abdominal pelvic irradiation and/or high dose chemotherapy * Surgery that requires removal of ovaries for medical condition or disease, e.g. Prophylactic oophorectomy in BRCA patients * Patient is unable or unwilling to pursue fertility preservation by freezing oocytes or embryos. * Previous treatment for cancer is acceptable if patient still has ovarian function * Patient is medically stable enough to undergo surgery (cleared for anesthesia) Exclusion Criteria: * Patients not meeting the above criteria * Patients who have not received medical clearance from their physicians to undergo surgery * Patients already experiencing menopause.
About the study
The study hopes to contribute to the development of technologies of ovarian tissue freezing-thawing and in vitro maturation of immature eggs such that a person at risk for premature ovarian failure might be able to conceive a genetically related child.
What is being tested
- surgery to remove ovaries or high dose chemotherapy (procedure)
Sponsor: Weill Medical College of Cornell University · Participants: 300 · Started: 1997-04
Contact the study team
- Rodriq E. Stubbs, NP · Phone: 646-962-3276
Official record on ClinicalTrials.gov — NCT01558544
Locations in the U.S.
| New York | Ronald O. Perelman and Claudia Cohen Center for Reproductive Medicine, New York |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.