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Cryopreservation of Ovarian Tissue

Recruiting

Cryopreservation of Ovarian Tissue for Potential In Vitro Maturation or Autologous Transplantation

Who can join

Up to age 45 · Women

Full eligibility criteria
Inclusion Criteria:

* Females 0-45 years of age who are premenopausal
* Treatment plan that will likely result in premature menopause or premature ovarian failure
* This includes patients receiving:
* Cancer treatment with abdominal pelvic irradiation and/or high dose chemotherapy
* Surgery that requires removal of ovaries for medical condition or disease, e.g. Prophylactic oophorectomy in BRCA patients
* Patient is unable or unwilling to pursue fertility preservation by freezing oocytes or embryos.
* Previous treatment for cancer is acceptable if patient still has ovarian function
* Patient is medically stable enough to undergo surgery (cleared for anesthesia)

Exclusion Criteria:

* Patients not meeting the above criteria
* Patients who have not received medical clearance from their physicians to undergo surgery
* Patients already experiencing menopause.

About the study

The study hopes to contribute to the development of technologies of ovarian tissue freezing-thawing and in vitro maturation of immature eggs such that a person at risk for premature ovarian failure might be able to conceive a genetically related child.

What is being tested

Sponsor: Weill Medical College of Cornell University · Participants: 300 · Started: 1997-04

Contact the study team

Official record on ClinicalTrials.gov — NCT01558544

Locations in the U.S.

New YorkRonald O. Perelman and Claudia Cohen Center for Reproductive Medicine, New York

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.