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Proton and Photon Consortium Registry (PPCR): A Multi Center Registry of Pediatric Patients Treated With Radiation Therapy

RecruitingObservational study

Who can join

Up to age 21 · All sexes

Full eligibility criteria
Eligibility Criteria:

1. Patients treated with radiation therapy at one of the participating centers
2. Age \< 22 at time of treatment start.
3. Patients may be enrolled regardless of previous local or systemic treatments received prior to enrollment in the PPCR.
4. Patients may be enrolled regardless of other current local or systemic treatments or disease extent.
5. Patients may be enrolled on the PPCR concurrently with another study or clinical trial.

About the study

In previous studies, Proton Beam Radiation Therapy (PBRT) has been found to show better results in treating patients with cancer, both because there is better control of where in the body the radiation is directed and because it is associated with less severe long term side effects. However, there is limited published data demonstrating these results. The goal of the Proton and Photon Consortium Registry (PPCR) is to enroll children treated with radiation in order to describe the population that currently receives radiation and better compare the short-term and long-term benefits of different types of radiotherapy. The data collected from this study will help facilitate research on radiation therapy and allow for collaborative research. The PPCR will collect demographic and clinical data that many centers that deliver radiation therapy already collect in routine operations.

What is being tested

Sponsor: Massachusetts General Hospital · Participants: 5,000 · Started: 2012-07

Contact the study team

Official record on ClinicalTrials.gov — NCT01696721

Locations in the U.S.

CaliforniaStanford University, Palo Alto
California Protons Cancer Therapy Center, San Diego
University of California San Francisco, San Francisco
FloridaUniversity of Florida Health Proton Therapy Institute, Jacksonville
GeorgiaEmory University, Atlanta
IllinoisNorthwestern Medicine Chicago Proton Center, Warrenville
MarylandMaryland Proton Treatment Center, Baltimore
MassachusettsMassachusetts General Hospital, Boston
MinnesotaMayo Clinic, Rochester
MissouriWashington University, St Louis
New JerseyProCure Proton Therapy Center- New Jersey, Somerset
New YorkNew York Proton Center, New York
State University of New York Upstate Medical Center, Syracuse
North CarolinaUniversity of North Carolina, Chapel Hill
OhioThe Ohio State University, Columbus
Cincinnati Children's Proton Therapy Center, Liberty Township
OklahomaOklahoma Proton Center, Oklahoma City
ProCure Proton Therapy Center- Oklahoma, Oklahoma City
PennsylvaniaUniversity of Pennsylvania - Roberts Proton Therapy Center, Philadelphia
TexasMD Anderson Cancer Center, Houston
Texas Center for Proton Therapy, Irving
UtahUniversity of Utah, Salt Lake City
WashingtonUniversity of Washington- Seattle Cancer Care Alliance, Seattle

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.