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Longitudinal Sexual and Reproductive Health Study of Women With Breast Cancer and Lymphoma

RecruitingObservational study

Who can join

Ages 18 and older · Women

Full eligibility criteria
Inclusion Criteria:

Subject Inclusion Criteria for Cohort of Premenopausal Women with Early Stage Breast Cancer and Lymphoma

* Women, 18 years of age and older
* Premenopausal women at time of diagnosis who have either been pregnant or had at least one menstrual period in the last 12 months

  * Note: premenopausal women at time of diagnosis who have not been pregnant or have not had at least one menstrual period in the last 12 months are able to participate only if they have had an intrauterine device (IUD) in place within the last 12 months.
* Women with newly diagnosed breast cancer (stage 0-III) who are within 1 month of starting systemic treatment or women with any aggressive lymphoma being treated with first line therapy with curative intent.
* Breast cancer patients with any receptor type
* English speaking
* Able to participate in the informed consent process

Subject Inclusion Criteria for Tamoxifen Only Subset of Cohort of Premenopausal Women with Early Stage Breast Cancer and Lymphoma

* Women, 18 years of age and older.
* Premenopausal women at time of diagnosis who have either been pregnant or had at least one menstrual period in the last 12 months

  * Note: premenopausal women at time of diagnosis who have not been pregnant or have not had at least one menstrual period in the last 12 months are able to participate only if they have had an intrauterine device (IUD) in place within the last 12 months.
* Women with newly diagnosed breast cancer (stage 0-III) who have not yet started treatment and are planning to start Tamoxifen as their only form of systemic treatment within one month
* Breast cancer patients with any receptor type
* English speaking
* Able to participate in the informed consent process

Subject Inclusion Criteria for Cohort of Postmenopausal Women with Early Stage Breast Cancer and Lymphoma

* Women, 18 years of age and older.
* Postmenopausal women at time of diagnosis who have been without period for ≥ 2 years.
* Women with newly diagnosed breast cancer (stage 0-III) who are within 1 month of starting systemic treatment or women with any aggressive lymphoma being treated with first line therapy with curative intent.
* Breast cancer patients with any receptor type
* English speaking
* Able to participate in the informed consent process

Exclusion Criteria:

Subject Exclusion Criteria for both Pre and Postmenopausal Women with Early Stage Breast Cancer and Lymphoma

* Active secondary cancer requiring cytotoxic chemotherapy
* Prior systemic treatment for a malignancy

About the study

The purpose of this study is to see how cancer treatment affects sexual and reproductive function. The patient will also be asked to participate in blood draws to see if and how cancer treatment affects the ovaries and the ability to have children (fertility). These blood draws are optional and the patient can still participate in the questionnaire portion of the study even if they choose not to have their blood drawn.

What is being tested

Sponsor: Memorial Sloan Kettering Cancer Center · Participants: 475 · Started: 2013-02

Contact the study team

Official record on ClinicalTrials.gov — NCT01788839

Locations in the U.S.

New JerseyMemorial Sloan Kettering Basking Ridge, Basking Ridge
Memorial Sloan Kettering Monmouth, Middletown
Memorial Sloan Kettering Bergen, Montvale
New YorkMemorial Sloan Kettering Commack, Commack
Memorial Sloan Kettering Westchester, Harrison
Memorial Sloan Kettering Cancer Center, New York
Memorial Sloan Kettering Nassau, Uniondale

Conditions

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.