🔎 Trials Near Me

Home › Scleroderma › NCT01808937

Morphea in Adults and Children (MAC) Cohort Study: A Morphea Registry and DNA Repository

RecruitingObservational studyHealthy volunteers welcome

Immunologic and Genetic Profiles in Subsets of Morphea Patients

Who can join

Up to age 90 · All sexes · Healthy volunteers welcome

Full eligibility criteria
Inclusion Criteria:

1. Patient must have a clinical diagnosis of morphea confirmed by the primary investigator and by histopathological examination.
2. Ages 0-90 years old
3. Children must weigh more than 20 lbs. in order to satisfy Children's Medical Center policy for the maximum amount of blood drawn in a 24 hour period.
4. Patient or legal guardian must be able to speak and read at a 6th grade reading level.
5. Both male and female patients will be eligible
6. All races and ethnic backgrounds will be included
7. Relationships to proband: All patients with morphea will be included. A patient's family history will be reviewed and if there is a family history of morphea or systemic sclerosis then we will give the study patient the investigator's contact information and ask the family member to call the study team to answer any questions and enroll them in the study if they choose to do so.
8. Ability to give informed consent: Patients must be able to give informed consent or they will give assent with parent or guardian consent as a minor to be a part of the morphea registry.

Exclusion Criteria:

\- Patients who have been coded as morphea (701.0), but do not have morphea/localized scleroderma (examples: steroid atrophy, acquired keratoderma, keloids, nephrogenic fibrosing dermopathy, systemic sclerosis, lichen sclerosis)

About the study

The Morphea in Adults and Children (MAC) cohort is the first registry for both children and adults with morphea (also known as localized scleroderma) in the country. The purpose of the registry is to learn more about morphea, specifically:

* How morphea behaves over time * How frequently specific problems occur along with morphea (for example, arthritis) * Whether morphea has an autoimmune background

What is being tested

Sponsor: University of Texas Southwestern Medical Center · Participants: 500 · Started: 2007-05

Contact the study team

Official record on ClinicalTrials.gov — NCT01808937

Locations in the U.S.

TexasUT Southwestern Medical Center - Department of Dermatology, Dallas

Conditions

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.