Study to Investigate Genetic Causes of Severe Early Childhood Onset Obesity.
Study to Identify Rare Genetic Variants Causing Severe Early Childhood Obesity
Who can join
Up to age 80 · All sexes
Full eligibility criteria
Inclusion Criteria: \- BMI \> 99th percentile documented at age \< 6 years of age Exclusion Criteria: * Known genetic causes of obesity * Known Endocrine causes of obesity. * Neurologic tumor, trauma or surgery * Prior malignancy or transplant * Known autoimmune diseases * Edema of a known or unknown cause * Prolonged steroid use.
About the study
This study aims to investigate genetic causes of early childhood obesity.
The investigators will enroll children and adults with severe early onset obesity (BMI \> 99th percentile) diagnosed prior to 6 years of age. The investigators will ask questions about the health and eating behavior of the participants, and perform a brief physical examination. The investigators will collect saliva or blood to perform genetic testing from the participants and invite family members to enroll in the study.
Sponsor: Columbia University · Participants: 500 · Started: 2014-02
Contact the study team
- Vidhu Thaker, M.D. · Phone: 212-851-5315
Official record on ClinicalTrials.gov — NCT01998750
Locations in the U.S.
| New York | Columbia University Medical Center, New York |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.