Home › Pancreatic Cancer › NCT02000089
The Cancer of the Pancreas Screening-5 CAPS5)Study
RecruitingPhase 3
Who can join
Ages 18 and older · All sexes
Full eligibility criteria
Inclusion Criteria: * Hereditary Pancreatitis or * Peutz-Jeghers Syndrome or * Strong family history of pancreas cancer on one side of the family tree or * Confirmed germline mutation carrier (BRCA2, FAMMM (CDKN2A/p16), PALB2, BRCA1, ATM, HNPCC, Lynch Syndrome (hMLH1, hMSH2, PMS2, hMSH6, EpCAM) PRSS1, PRSS2, R122H, N291l, SPINK1, CFTR * Endoscopic evaluation of pancreas scheduled Exclusion Criteria: * Medical comorbidities or coagulopathy that contraindicate endoscopy * Prior surgery that prevent optimal endoscopic ultrasound such as partial or complete gastrectomy with Bilroth or Roux-en-Y anastomosis * Stricture or obstruction in the upper GI tract that does not allow passage of the echoendoscope * Poor performance status * Inability to provide informed consent * Pregnancy.
About the study
Johns Hopkins clinical research office quality assurance group will monitor and audit this study at Johns Hopkins. The Sub Investigator at each site will be responsible for internal monitoring at their site.
What is being tested
- Secretin (drug)
- MRI (diagnostic test)
- Tumor marker gene test with CA19-9 (other)
Sponsor: Johns Hopkins University · Participants: 9,000 · Started: Jan 6, 2014
Contact the study team
Official record on ClinicalTrials.gov — NCT02000089
Locations in the U.S.
Conditions
- Pancreatic Cancer
- Hereditary Nonpolyposis Colorectal Cancer
- Breast Cancer
- Hereditary Sensory and Autonomic Neuropathies
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.