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Metabolic Biomarkers in Thoracic Cancers

Who can join

Ages 18 and older · All sexes

Inclusion Criteria:

1. Patients must have known or probable malignant lesions requiring surgical biopsy or excision.
2. Subjects of all races and ethnic origins over 18 years of age.

Exclusion Criteria:

1. Not a surgical candidate.
2. Poorly controlled diabetes.

About the study

The purpose of this research study is to develop a method of using magnetic resonance imaging (MRI) to evaluate lung tumors and other thoracic malignancies. An MRI is a scanning device that uses magnets to make images (pictures) of the body. This study is being done to determine what series of reactions (metabolic pathways) pulmonary nodules use as they burn sugar as fuel for growth. The manner in which the tumor burns (metabolizes) sugar for fuel is being investigated by using a natural, slightly modified, sugar solution (13C-glucose) and studying a small sample of the tumor once it is removed at the time of surgery.

What is being tested

• Imaging Biomarkers (procedure)

Sponsor: University of Texas Southwestern Medical Center · Participants: 200 · Started: Mar 20, 2013

Contact the study team

• Ebele Mbanugo, Ed.D, CCRP · Phone: 214-648-7097

Official record on ClinicalTrials.gov — NCT02095808

Locations in the U.S.

Conditions

• Lung Cancer

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.