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Improving Bladder Function in SCI by Neuromodulation

Recruiting

Who can join

Ages 18 to 45 · Men

Full eligibility criteria
Inclusion Criteria:

1. Male 18-45 years;
2. At least 1 year post-injury;
3. Non-progressive SCI at C2-T8 (non-conus injury);
4. Motor Complete ASIA (A or B);
5. Neurogenic bladder requiring clean intermittent straight catheterization;
6. Able to attend twice weekly testing sessions for 6 months.
7. Have intact lower extremity anatomy and able to use lower extremity for assistive standing and stepping.

Exclusion Criteria:

1. History of autonomic dysreflexia;
2. Ventilator dependency;
3. Musculoskeletal dysfunction, unhealed fracture, pressure ulcer, active infection;
4. Clinically significant depression or ongoing drug abuse;
5. Received botox injection, or bladder surgery (suprapubic access, Brindley procedure, etc.); 6. Prostatic hypertrophy or bladder outlet disorder;

7\. Cardiopulmonary disease that precludes lower extremity training or rehabilitation.

About the study

This trial will investigate the safety and utility of spinal cord neuromodulation to improve urinary bladder function in the context of spinal cord injury.

What is being tested

Sponsor: University of California, Los Angeles · Participants: 24 · Started: 2015-09

Contact the study team

Official record on ClinicalTrials.gov — NCT02331979

Locations in the U.S.

CaliforniaUniversity of California, Los Angeles, Los Angeles

Conditions

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.