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Genomic Predictors of Papillary Microcarcinoma Disease Progression

Who can join

Ages 18 and older · All sexes

Inclusion Criteria:

* Biopsy proven papillary thyroid cancer (or suspicious for papillary thyroid cancer) confirmed by MSKCC cytopathologist.
* Being followed with active surveillance at MSKCC
* Biopsied index nodule less than or equal to 2 cm in maximum dimension
* Thyroid and neck US performed and interpreted by a MSKCC radiologist within 6 months prior to study entry.

Exclusion Criteria:

* Biopsied index nodule greater than 2 cm in any dimension
* Age less than 18 yrs old

About the study

The study is being done to answer the following question: What are the specific clinical and molecular features that will help us predict which small thyroid cancers are likely to grow and be problematic?

Therefore, the purpose of this study is to identify specific clinical and molecular characteristics that are predictive of tumor progression in small thyroid cancers.

Sponsor: Memorial Sloan Kettering Cancer Center · Participants: 750 · Started: Dec 31, 2014

Contact the study team

• Robert Tuttle, MD · Phone: 646-888-2716
• Michael Berger, PhD · Phone: 646-888-3386

Official record on ClinicalTrials.gov — NCT02363595

Locations in the U.S.

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.