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Magnetic Resonance Elastography in Patients With Abdominal Aortic Aneurysms

RecruitingObservational studyHealthy volunteers welcome

Who can join

Ages 20 and older · All sexes · Healthy volunteers welcome

Full eligibility criteria
Inclusion Criteria:

* Must be able to lie flat on their back in the scanner for up to 60 minutes
* Must be able to hold breath for up to 15 seconds

Exclusion Criteria:

* Patients who are claustrophobic
* Patients who are pregnant
* Patients with any unapproved, non-MRI save metal/devices in or on their body

About the study

The main objective of this study is to utilize Magnetic Resonance Elastography (MRE) to determine tissue stiffness of abdominal aortic aneurysms (AAA). For patients with AAA, MRE is a more sensitive and superior method of determining the risk for rupture of AAA based on stiffness estimates when compared to the current, crude method of assessing risk based on measurement of the diameter of the aneurysm. The investigators will also validate the stiffness estimates against gold standard i.e. mechanical testing and histopathology only AAA patients undergoing AAA surgery.

What is being tested

Sponsor: Ohio State University · Participants: 165 · Started: 2014-10

Contact the study team

Official record on ClinicalTrials.gov — NCT02387255

Locations in the U.S.

OhioThe Ohio State University Medical Center, Columbus

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.