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Biomarkers in Infection

Early Detection of Inflammatory Biomarkers in Infection

Who can join

Ages 18 and older · All sexes · Healthy volunteers welcome

Inclusion Criteria for Infected subjects:

* Age 18 years of age or older
* Confirmed or suspected infection

Inclusion Criteria for Control Subjects:

* Age 18 years of age or older
* A non-infectious clinical presentation to include
* Normal white blood cell count ( \> 4,000 and/or \< 12,000)
* Normothermia ( \> 96.5 and/or less 100.4)
* Absence of the following clinical complaints: productive cough, fever, pyuria, rash
* No evidence of acute coronary syndrome

Exclusion Criteria for Control Subjects:

\- Suspected infection

About the study

The purpose of this investigation is to evaluate how early biomarkers of infection and inflammation perform in identifying patients at risk for poor outcome in sepsis and septic shock.

Sponsor: Beth Israel Deaconess Medical Center · Participants: 4,200 · Started: 2006-04

Contact the study team

• Nathan Shapiro, MD MPH · Phone: 617-754-2343
• Carlo Ottanelli, BSc · Phone: 617-650-0042

Official record on ClinicalTrials.gov — NCT02545478

Locations in the U.S.

Conditions

• Sepsis
• Septic Shock

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.