Home › Autosomal Dominant Polycystic Kidney › NCT02936791

Early PKD Observational Cohort Study

Who can join

Ages 4 to 35 · All sexes · Healthy volunteers welcome

Inclusion Criteria:

* Inclusion for early stage autosomal dominant polycystic kidney disease (ADPKD):

  * Family history of PKD
  * All races and ethnic groups
  * Glomerular filtration rate (GFR) \>80 ml/min per 1.73 m2
* Inclusion for Healthy Volunteers:

  * Male or female with no family history of kidney disease
  * All races and ethnic groups
  * Normal GFR

Exclusion Criteria:

* Non-insulin or insulin-dependent diabetes mellitus
* Systemic illness (i.e.systemic lupus erythematosus, vasculitis)
* Unable to provide written informed consent
* Unavailable for magnetic resonance imaging (MRI) and blood/urine collection

About the study

This observational study will collect blood and urine and clinical information from individuals with early-stages of polycystic kidney disease (PKD), their unaffected siblings and normal volunteers to create a biobank, also called a biorepository. The long-term goal is to develop new knowledge on biological markers or biomarkers that indicate changes in the disease progression. An understanding of biomarkers for early renal cyst growth will benefit PKD patients as new therapies are being developed and tested.

Sponsor: University of Kansas Medical Center · Participants: 250 · Started: 2016-04

Contact the study team

• Cathy Creed, RN · Phone: 913-588-0053

Official record on ClinicalTrials.gov — NCT02936791

Locations in the U.S.

Conditions

• Autosomal Dominant Polycystic Kidney

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.