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Regulation of Inflammatory Genes in Psoriasis

Who can join

Ages 19 to 99 · All sexes · Healthy volunteers welcome

Inclusion Criteria:

* Clinical diagnosis of psoriasis
* Must be age 19 or older.
* Must be Fitzpatrick skin type I, II, III, IV, V, VI.

Exclusion Criteria:

* Subjects who do not have photosensitive disease and are not on photosensitizing medications.
* Subjects with a history of keloids (who are more likely to develop hypertrophic scars following skin biopsy).
* Subjects who have an allergy to local anesthetics, antibiotics and/or anticoagulants.
* Subjects who are pregnant.

About the study

Psoriasis is a chronic and recurrent skin disorder characterized by marked inflammatory changes in the skin. An extensive cytokine network including generated by activated dendritic cells and T cells mediates the formation of psoriatic lesions. These immune-response parameters can be used as markers in the severity and management of the disease after further in-depth studies.

What is being tested

• Inflammatory markers (diagnostic test)

Sponsor: University of Alabama at Birmingham · Participants: 13 · Started: Apr 22, 2014

Contact the study team

Official record on ClinicalTrials.gov — NCT03125655

Locations in the U.S.

Conditions

• Psoriasis

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.