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Plantar Fasciitis Randomized Clinical Control Trial
Randomized Clinical Study to Evaluate Ultrasound Guided Injection Therapy Versus Topographic Injection Therapy for Plantar Fasciitis
Who can join
Ages 18 and older · All sexes · Healthy volunteers welcome
Full eligibility criteria
Inclusion Criteria: * Pain on palpation along the proximal plantar fascia with or without radiographic evidence of a plantar calcaneal bone spur * ≥18 years of age * Male or non-pregnant female of any ethnicity or race * Active, former or non smoker * With or without peripheral vascular disease without lower extremity intermittent claudication or rest pain * With or without diabetes mellitus without polyneuropathy * With or without collagen vascular disease without lower extremity wound formation. Exclusion Criteria: * Known drug or alcohol dependence * Chronic pain syndrome or lumbosacral radiculitis * Neurological condition that requires the use of analgesic medications or anti-seizure or neuroleptic medications * Peripheral vascular disease that results in rest pain or intermittent claudication or venous stasis ulceration * Calcaneal stress fracture or show evidence of a foreign body or tumor of the affected heel as viewed radiographically * Pregnant females * Known allergy to any of the components of the injection therapy * Previously suffered a rupture or surgery of the plantar fascia within the 5 years preceding participation in the investigation * Existing or prior osteomyelitis of the involved calcaneus * Unable to consent to participation in clinical research or currently be involved in another clinical investigation.
About the study
The primary aim of this clinical experiment is to compare, in terms of pain relief measured using the 10-cm visual analog scale (VAS) pain score (5-7), the clinical results of ultrasound-guided injection (USGI) versus anatomic topography-guided injection (ATGI) of corticosteroid for the treatment of proximal PF. Secondary aims will be to compare foot-related quality of life, as measured using the Foot Function Index (FFI)and the Bristol Foot Score (BFS), between the injection groups, and also to compare the pre-injection to late-term post-injection thickness of the plantar fascia as measured in the nested USGI group.
What is being tested
- Local Steroid Injection into the plantar heel (procedure)
- Ultrasound Guided Injection (procedure)
- Anatomical Guided injection (procedure)
Sponsor: University of Pennsylvania · Participants: 62 · Started: Mar 28, 2017
Contact the study team
- Donald S Malay, DPM · Phone: 4848440755
- Hye R Kim, DPM · Phone: 443-765-6588
Official record on ClinicalTrials.gov — NCT03231150
Locations in the U.S.
| Pennsylvania | Penn Presbyterian Medical Center, Philadelphia |
From ClinicalTrials.gov, data retrieved Oct 2, 2026. Each study sets its own eligibility; the study team decides who can join.